Results 131 to 140 of about 16,408 (292)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Clinical Ophthalmology, 2017 Ahmed Abdel-Karim El-Massry, Amgad Mostafa Dowidar, Tamer Hamdy Massoud, Baher Guirguis Daoud Tadros Department of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria Governorate, Egypt Background: Corneal collagen cross-linking (CXL)
El-Massry AA +3 more
doaj
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
A note on minimum aberration and clear criteria
Minimum aberration and clear criteria are two important rules for selecting optimal fractional factorial designs, in both unblocked and blocked cases. In this paper, we first show that under some given conditions, a blocked design DB=(D,B) having blocked
Liu, Min-Qian +3 more
core
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
A connection between uniformity and aberration in regular fractions of two-level factorials
, 2000 We show a link between the two apparently unrelated areas of uniformity and minimum aberration. With reference to regular fractions of two-level factorials, we derive an expression for the centred L2-discrepancy measure for uniformity in terms of the ...
Mukerjee, R., Fang, K. T.
core +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Construction of fractional factorial split-plot designs with weak minimum aberration
Fractional factorial split-plot (FFSP) designs with minimum aberration have been applied in industrial experiments. But, they are not so easy to construct for cases having many whole plot (or subplot) factors and only few subplot (or whole plot) factors.
Zhang, Runchu +2 more
core
Geometric isomorphism and minimum aberration for factorial designs with quantitative factors
, 2011 [[abstract]]Factorial designs have broad applications in agricultural, engineering and scientific studies. In constructing and studying properties of factorial designs, traditional design theory treats all factors as nominal.
Cheng SW;Ye KQ
core +1 more source