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The Minimum Alveolar Concentration of Nitrous Oxide in Man
Anesthesia & Analgesia, 1982The potency and anesthetic state produced by nitrous oxide alone were investigated in order to clarify its contribution to the effect of other anesthetic agents. Seven volunteers anesthetized with 1.55 atm absolute N2O in a pressure chamber displayed muscle rigidity with jerking movements, labored and rapid breathing, sweating, and dilated pupils. At 1.
T F, Hornbein +5 more
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The Minimum Alveolar Concentration (MAC) of Sevoflurane in Humans
Anesthesiology, 1987Forty surgical patients were divided into two groups and anesthetized with either sevoflurane and oxygen or sevoflurane, oxygen, and nitrous oxide. The minimum alveolar concentration (MAC) for sevoflurane required to prevent movement in response to surgical incision in healthy patients was 1.71 +/- 0.07% (SE).
T, Katoh, K, Ikeda
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Cardiopulmonary bypass reduces the minimum alveolar concentration for isoflurane
Journal of Cardiothoracic and Vascular Anesthesia, 2004The purpose of this investigation was to determine the influence of cardiopulmonary bypass (CPB) on the minimum alveolar concentration (MAC) of isoflurane in a rat model of CPB.Prospective.University research laboratory.Sprague-Dawley rats.Using tail-clamp methodology, the pre- and post-CPB MAC for isoflurane was studied.Rats were anesthetized with ...
Hong, Yang +3 more
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Minimum alveolar concentration of desflurane in llamas and alpacas
Veterinary Anaesthesia and Analgesia, 2006To determine the minimum alveolar concentration (MAC) of desflurane in llamas and alpacas.Prospective study. Animals Six healthy adult llamas and six healthy adult alpacas.Anesthesia was induced with desflurane delivered with oxygen through a mask.
Tamara L, Grubb +6 more
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Minimum Alveolar Concentration (MAC)
Abstract Minimum alveolar concentration (MAC) serves as a marker of anesthetic depth while using a volatile anesthetic, and allows for comparison of the potencies between different volatile anesthetic agents. MAC value has a specific definition, and there is clinical significance to varying MAC values, such as MAC-aware and MAC-BAR ...Hao Hua, Daniel S. Cormican
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Minimum Alveolar Anesthetic Concentrations for Airway Occlusion in Cats
Anesthesia & Analgesia, 1998Minimum alveolar anesthetic concentration (MAC) is defined as an end-tidal concentration of inhaled anesthetic required to prevent purposeful movement (positive motor response) in 50% of subjects to somatic noxious stimuli. Although MAC for visceral noxious stimuli has not been well investigated, airway occlusion can be a noxious respiratory stimulus ...
T, Ide, Y, Sakurai, M, Aono, T, Nishino
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Flumazenil Decreases the Minimum Alveolar Concentration of Isoflurane in Dogs
Anesthesiology, 1989Flumazenil is a potent-specific benzodiazepine receptor antagonist that has been shown to reverse CNS depressant effects mediated by benzodiazepine agonists. These agonists are known to affect the interaction of gamma aminobutyric acid (GABA) with its receptor.
A E, Schwartz +4 more
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Minimum Alveolar Anesthetic Concentration of Isoflurane with Different Xenon Concentrations in Swine
Anesthesia & Analgesia, 2003For patients requiring a fraction of inspired oxygen more than 0.3, the use of xenon (Xe) as the sole anesthetic is limited because of its large minimum alveolar anesthetic concentration (MAC) of 71%. This warrants investigating the combination of Xe with other inhaled anesthetics. We therefore investigated the influence of Xe on the MAC of isoflurane.
Klaus E, Hecker +5 more
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From individual to population: the minimum alveolar concentration curve
Current Opinion in Anaesthesiology, 2006The concept of minimum alveolar concentration is central to the study of inhalational anesthetics. The minimum alveolar concentration curve is a population concentration-response curve that describes the relationship between anesthetic concentration and oblation of the movement response to painful stimuli.
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Determination of the Minimum Alveolar Concentration of Isoflurane in Llamas
Veterinary Surgery, 1999Objective—To determine the minimum alveolar concentration (MAC) of isoflurane (ISO) in llamas.Study Design—Prospective study.Animals—Eight adult neutered male llamas (9 ± 1 years [x̄± SD], 177 ± 29 kg).Methods—Anesthesia was induced and maintained in otherwise unmedicated llamas with a mixture of ISO in oxygen administered through a standard small ...
K R, Mama +4 more
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