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Determination of the Minimum Alveolar Concentration (MAC) of Aliflurane in Dogs
Anesthesiology, 1979The minimum alveolar concentration (MAC) of aliflurane was measured in ten dogs. A value of 1.84 volumes per cent was determined, which correlates well with predictions based on lipid solubility. Induction of anesthesia and recovery were rapid, as would be anticipated with an agent of relatively low solubility in blood (blood-gas partition coefficient =
Lawrence G. Kushins+4 more
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A Method for Determining Minimum Alveolar Concentration of Anesthetic in the Rat
Anesthesiology, 1973Minimum alveclir concentrations (MAC) for halothane and methoxyflurane were determined at two stimulus intensities in the rat. Forty-three rats were anesthetized with halothane or methoxyflurane in oxygen, and after tracheostomy were ventilated with a Harvard Rodent Respirator.
Louis R. Orkin+2 more
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Effects of tramadol on the minimum alveolar concentration of sevoflurane in dogs
Veterinary Anaesthesia and Analgesia, 2009To evaluate the effect of tramadol on sevoflurane minimum alveolar concentration (MAC(SEVO)) in dogs. It was hypothesized that tramadol would dose-dependently decrease MAC(SEVO).Randomized crossover experimental study.Six healthy, adult female mixed-breed dogs (24.2 +/- 2.6 kg).Each dog was studied on two occasions with a 7-day washout period ...
Thomas J Doherty+4 more
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The effect of buprenorphine on isoflurane minimum alveolar concentration in dogs
, 2014Objective To determine the effect of intravenous (IV) buprenorphine on the isoflurane (ISO) minimum alveolar concentration (ISOMAC) in dogs. Study design Randomized, crossover, design.
P. Queiroz-Williams+4 more
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Minimum Alveolar Concentration of Sevoflurane in Rabbits with Liver Fibrosis
Anesthesia & Analgesia, 2012Sevoflurane is widely used in patients undergoing surgical procedures, which could affect both the liver function and hepatic blood flow. However, the effects of liver fibrosis on minimum alveolar concentration (MAC) of sevoflurane are still unclear. Therefore, we designed this study to determine the MAC of sevoflurane in rabbits with liver fibrosis ...
Ming Yan, Yan Yin, Tao Zhu
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Minimum alveolar concentration and lipid solubility
2006Minimum alveolar concentration (MAC) is defined as such a concentration of a volatile anaesthetic agent that produces immobility in 50% of experimental animals subjected to a standardized noxious stimulus. It resembles ED 50 for intravenous drugs, and serves the same purpose: comparison of the potencies of various drugs.
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Comparison of halothane minimum alveolar concentration and minimum effective concentration in ponies
Journal of Veterinary Pharmacology and Therapeutics, 1997Donita L. Frazier+2 more
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Veterinary Anaesthesia and Analgesia, 2019
B. Pypendop, H. Ahokoivu, J. Honkavaara
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B. Pypendop, H. Ahokoivu, J. Honkavaara
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