Age, Minimum Alveolar Anesthetic Concentration, and Minimum Alveolar Anesthetic Concentration-Awake
Two defining effects of inhaled anesthetics (immobility in the face of noxious stimulation, and absence of memory) correlate with the end-tidal concentrations of the anesthetics. Such defining effects are characterized as MAC (the concentration producing immobility in 50% of patients subjected to a noxious stimulus) and MAC-Awake (the concentration ...
Edmond I. Eger
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Increasing plasma ketamine concentrations decrease the minimum alveolar concentration of isoflurane in rabbits [PDF]
To evaluate the effects of increasing plasma ketamine concentration on isoflurane minimum alveolar concentration (MAC) in rabbits, six New Zealand white rabbits weighing 4.21 ± 0.35 kg were anesthetized with isoflurane in oxygen.
Linda S. Barter, Bruno H. Pypendop
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We evaluated the effects of i.v. adenosine triphosphate (ATP) on sevoflurane minimum alveolar anesthetic concentration (MAC) and MAC-Awake. The study group included healthy patients 20-60 yr of age. The study groups for MAC-Awake determination included 49 patients who were scheduled for elective surgery.
Akira Suzuki+2 more
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Effects of mild cognitive impairment and sleep disorders on the minimum alveolar concentration value of sevoflurane [PDF]
Objectives To explore the effect of mild cognitive impairment (MCI) and MCI with sleep disorders on the potency of sevoflurane anesthesia in the elderly. Design Prospective study methods. Dixon up-and-down methods.
Lei Wang+3 more
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Age-dependent decrease in minimum alveolar concentration of inhaled anaesthetics: a systematic search of published studies and meta-regression analysis. [PDF]
Cooter M+8 more
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Effects of lidocaine, dexmedetomidine or their combination on the minimum alveolar concentration of sevoflurane in dogs. [PDF]
The aim of this study was to determine the effects of lidocaine (LIDO) and dexmedetomidine (DEX) or their combination (LIDO–DEX), administered by constant-rate infusion (CRI), on the minimum alveolar concentration (MAC) of sevoflurane in dogs.
Moran-Muñoz R+7 more
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A study of the relationship between Bispectral index and age-adjusted minimum alveolar concentration during the maintenance phase of general anesthesia in elective surgery [PDF]
Background and Aims: Bispectral index (BIS) and minimum alveolar concentration (MAC) are commonly used to monitor the depth of anesthesia. The objective was to study the correlation between BIS and age-adjusted minimum alveolar concentration (aaMAC ...
Nishant Kumar, Gunjan Bansal, Aruna Jain
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Paradox of age: older patients receive higher age-adjusted minimum alveolar concentration fractions of volatile anaesthetics yet display higher bispectral index values. [PDF]
Ni K+8 more
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Minimum Alveolar Concentration (MAC) of Xenon with Sevoflurane in Humans [PDF]
Background Although more than 30 yr ago the minimum alveolar concentration (MAC) of xenon was determined to be 71%, that previous study had technological limitations, and no other studies have confirmed the MAC value of xenon since.
Yoshinori Nakata+7 more
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Minimum Alveolar Anesthetic Concentration [PDF]
Edmond I. Eger+2 more
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