Review of hypoxaemia in the anaesthetized horse: predisposing factors, consequences and management [PDF]
, 2017 Objectives: To discuss how hypoxaemia might be harmful and why the horse is particularly predisposed to developing it. To review the strategies that are used to manage hypoxaemia in anaesthetised horses, to describe how successful these strategies are
Auckburally, Adam, Nyman, Görel
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Intrathecal Veratridine Administration Increases Minimum Alveolar Concentration in Rats [PDF]
Anesthesia & Analgesia, 2008 Results from several studies point to sodium channels as potential mediators of the immobility produced by inhaled anesthetics. We hypothesized that the intrathecal administration of veratridine, a drug that enhances the activity or effect of sodium channels, should increase MAC.We measured the change in isoflurane MAC caused by intrathecal infusion of
Yi, Zhang +5 more
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Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury. [PDF]
, 2018 BACKGROUND: Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2.
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Ethane-beta-Sultam Modifies the Activation of the Innate Immune System Induced by Intermittent Ethanol Administration in Female Adolescent Rats [PDF]
, 2014 Intermittent ethanol abuse or ‘binge drinking’ during adolescence induces neuronal damage, which may be associated with cognitive dysfunction. To investigate the neurochemical processes involved, rats were administered either 1 g/kg or 2 g/kg ethanol in ...
Colivicchi, M.A. +10 more
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Short versus long silver nanowires: a comparison of in vivo pulmonary effects post instillation. [PDF]
, 2014 BackgroundSilver nanowires (Ag NWs) are increasingly being used to produce touchscreens for smart phones and computers. When applied in a thin film over a plastic substrate, Ag NWs create a transparent, highly-conductive network of fibers enabling the ...
Anderson, Donald S +8 more
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Does trazodone reduce anaesthetic agent requirement in dogs?
Veterinary Evidence, 2022 PICO question In dogs undergoing anaesthesia, does the use of oral trazodone given 2 hours before induction of anaesthesia reduce injectable or inhalant anaesthetic agent requirements?
Gemma Stewart
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Desflurane Selectively Suppresses Long-latency Cortical Neuronal Response to Flash in the Rat [PDF]
, 2009 Background—The effect of inhalational anesthetics on sensory-evoked unit activity in the cerebral cortex has been controversial. Desflurane has desirable properties for in vivo neurophysiologic studies but its effect on cortical neuronal activity and ...
Hudetz, Anthony G. +2 more
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Hearts, 2021 Background and Aims: We hypothesized that maintaining a patient on moderate–high doses of potent inhalational agent for greater than 30 min during the post-bypass period would be an independent predictor of initiation and usage of either inotropic and/or
Tara A. Lenk +6 more
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Investigating the suitability of high content image analysis as a tool to assess the reversibility of foamy alveolar macrophage phenotypes in vitro. [PDF]
, 2020 Many potential inhaled medicines fail during development due to the induction of a highly vacuolated or “foamy” alveolar macrophage phenotype response in pre-clinical studies.
Hoffman, Ewelina +2 more
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A finite membrane element formulation for surfactants
, 2019 Surfactants play an important role in various physiological and biomechanical applications. An example is the respiratory system, where pulmonary surfactants facilitate the breathing and reduce the possibility of airway blocking by lowering the surface ...
Roohbakhshan, Farshad, Sauer, Roger A.
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