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Minimum Bactericidal Concentration Techniques in Mycobacterium tuberculosis: A Systematic Review
Microbial Drug Resistance, 2020Minimum bactericidal concentration (MBC) assay is an accepted parameter for evaluating new antimicrobial agents, and it is frequently used as a research tool to provide a prediction of bacterial eradication. To the best of our knowledge, there is no standardization among researchers regarding the technique used to detect a drug's MBC in Mycobacterium ...
Nathally Claudiane de Souza, Santos +11 more
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Journal of Antimicrobial Chemotherapy, 1985
Minimal bactericidal concentrations (MBCs) of nine antimicrobial agents were determined for clinical isolates by a replica plating method. Membranes were placed on the antibiotic-containing plates and the organisms replicated onto the membranes. After 18 h incubation the minimal inhibitory concentrations (MICs) were determined, the membranes were ...
Clarence J. Fernandes +4 more
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Minimal bactericidal concentrations (MBCs) of nine antimicrobial agents were determined for clinical isolates by a replica plating method. Membranes were placed on the antibiotic-containing plates and the organisms replicated onto the membranes. After 18 h incubation the minimal inhibitory concentrations (MICs) were determined, the membranes were ...
Clarence J. Fernandes +4 more
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Peak Concentration in Serum to Minimum Bactericidal Concentration
Archives of Internal Medicine, 1980The clinical science of antimicrobial pharmacology has been extraordinarily useful in guiding treatment of patients with life-threatening bacterial infections. When the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the antibacterial agent used has been ≤1 μg/mL, and peak concentration of drug in serum has been ...
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Veterinary Microbiology, 2011
Tiamulin activity was measured against 19 UK field isolates of Actinobacillus pleuropneumoniae collected between 2003 and 2009 and the type strain ATCC 27090 as a control, with the intention of comparing broth with serum as growth media. Broth microdilution MIC/MBC tests were performed in accordance with the Clinical and Laboratory Standards Institute (
Andrew, Pridmore +2 more
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Tiamulin activity was measured against 19 UK field isolates of Actinobacillus pleuropneumoniae collected between 2003 and 2009 and the type strain ATCC 27090 as a control, with the intention of comparing broth with serum as growth media. Broth microdilution MIC/MBC tests were performed in accordance with the Clinical and Laboratory Standards Institute (
Andrew, Pridmore +2 more
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Future Microbiology, 2020
Aim: To evaluate an assay to detect minimum bactericidal concentration (MBC) in Mycobacterium tuberculosis, using as single model rifampicin, isoniazid, levofloxacin (LVX) and linezolid (LNZ) and in combination. Material & methods: MBCs were carried out directly from resazurin microtiter assay plate and 3D checkerboard in M. tuberculosis H37Rv and five
Nathally C de S Santos +14 more
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Aim: To evaluate an assay to detect minimum bactericidal concentration (MBC) in Mycobacterium tuberculosis, using as single model rifampicin, isoniazid, levofloxacin (LVX) and linezolid (LNZ) and in combination. Material & methods: MBCs were carried out directly from resazurin microtiter assay plate and 3D checkerboard in M. tuberculosis H37Rv and five
Nathally C de S Santos +14 more
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Journal of Chemotherapy, 1989
The in vitro activity of tigemonam, a new oral monobactam, was studied with special attention to minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs). Against 250 clinical isolates, it inhibited 100% of Escherichia sp., Klebsiella sp., Serratia sp., Citrobacter sp., Providencia sp., Proteus sp., Morganetta sp ...
M, Gobernado, E, Cantón
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The in vitro activity of tigemonam, a new oral monobactam, was studied with special attention to minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs). Against 250 clinical isolates, it inhibited 100% of Escherichia sp., Klebsiella sp., Serratia sp., Citrobacter sp., Providencia sp., Proteus sp., Morganetta sp ...
M, Gobernado, E, Cantón
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Indian Journal of Public Health Research & Development, 2019
Streptococcus pyogenes one cause of respiratory tract infections including pharyngitis. Seventy-three percent of doctors prescribe antibiotics for pharyngitis. In developing countries, antibiotics are prescribed for 44–97% of hospitalized patients, sometimes with inappropriate doses.
Ratih Dewi Dwiyanti +2 more
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Streptococcus pyogenes one cause of respiratory tract infections including pharyngitis. Seventy-three percent of doctors prescribe antibiotics for pharyngitis. In developing countries, antibiotics are prescribed for 44–97% of hospitalized patients, sometimes with inappropriate doses.
Ratih Dewi Dwiyanti +2 more
openaire +1 more source

