Results 61 to 70 of about 99,604 (299)

A method for determining the characteristics of the steady creep of a single crystal alloy

Авіаційно-космічна техніка та технологія, 2022
The subject of this article is the phenomenon of material destruction during creep, as one of the most dangerous and damaging effects on turbine blades in the conditions of their operation.
Yevhen Nemanezhyn, Gennadiy Lvov, Yuriy Torba   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Short-term creep approach to redefining the role of 17-4PH stainless steel for high-temperature applications

Scientific Reports
The creep response of the 17-4PH martensitic age-hardening steel in H1150 state was investigated at 427 and 482 °C. Hardness measurements of the heads of the creep samples demonstrated that the material underwent additional age hardening during the high ...
S. Spigarelli, M. Cabibbo, A. Santoni, E. Santecchia   +3 more
doaj   +1 more source

Enhanced creep resistance of Y-bearing 9Cr ferritic/martensitic steel via vacuum casting technique

Journal of Materials Research and Technology, 2019
9Cr ferritic/martensitic (F/M) steels with 0 and 0.3 wt.% yttrium (Y) addition were fabricated via vacuum casting technique and were creep tested at 650 °C and 120 MPa. The creep property of 9Cr F/M steel was improved by the addition of yttrium.
Yingxue Chen, Zhiyuan Hong, Xiaoxin Zhang, Min Xia, Qingzhi Yan, Changchun Ge   +5 more
doaj   +1 more source

Creep-fatigue life assessment of cruciform weldments using the linear matching method [PDF]

, 2013
This paper presents a creep-fatigue life assessment of a cruciform weldment made of the steel AISI type 316N(L) and subjected to reversed bending and cyclic dwells at 550C using the Linear Matching Method (LMM) and considering different weld zones.
Chen, Haofeng, Gorash, Yevgen
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

The role of particle ripening on the creep acceleration of Nimonic 263 superalloy

MATEC Web of Conferences, 2014
Physically based constitutive equations need to incorporate the most relevant microstructural features of materials to adequately describe their mechanical behaviour. To accurately model the creep behaviour of precipitation hardened alloys, the value and
Angella Giuliano, Donnini Riccardo, Ripamonti Dario, Maldini Maurizio   +3 more
doaj   +1 more source

A Minimum Creep Rate for 2-1/4Cr-1Mo Steel Consistent With the ASME Section III, Division 5 Rules

Journal of Pressure Vessel Technology, 2021
Abstract This technical note describes a minimum creep rate model for 2-1/4Cr-1Mo steel that is consistent with the current creep strain equation embedded in the ASME Boiler & Pressure Vessel Code Section III, Division 5, Subsection HB, Subpart B isochronous stress–strain curves.
Aritra Chakraborty, Mark C. Messner, T.-L. Sham   +2 more
openaire   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Preearthquake and Postearthquake Creep on the Imperial Fault and the Brawley Fault Zone [PDF]

, 1982
Taken together, 12 years of alinement-array data, 4 years of creepmeter records from four instruments, and 2 years of surveys from two nail files suggests that creep events on the Imperial fault 2 to 5 months before the October 15 earthquake are ...
Allen, Clarence R., Cohn, Stephen N., Gilman, Ralph, Goulty, Neil R.   +3 more
core