Results 51 to 60 of about 16,947,670 (194)

Identification of spatial pathways for aquatic ecological risk spread under multi-stressor synergies: A case study of the Pinglu Canal

Ecological Indicators
Multiple stressors in aquatic ecosystems can interact to amplify risks and drive their spread across space. Conventional single-stressor models overlook these dynamics, impeding the identification of risk spatial spread pathways (RSSPs) and evidence ...
Naixin Yin, Ruijing Qiao, Zhenghong Liang, Wangye Lu, Luming Liu, Jiaxue Ji, Ronghua Zhong, Feiling Yang, Jie Li   +8 more
doaj   +1 more source

Plasmid maps of pACYC-Para-MCR-1 and pACYC-NP-MCR-1.

, 2023
The plasmid for expressing MCR-1 or M6 under the regulation of arabinose promoter was shown as (A), and the one for expressing target proteins under the regulation of MCR-1 native promoter was shown as (B).
Chenchen Zhang (324804), Siyuan Feng (5998040), Yaxin Li (312731), Lingxuan Lyu (17628265), Yohei Doi (188766), Wanfei Liang (8610954), Fang Bai (1612534), Lin Wang (11986), Lan-Lan Zhong (9702537), Dianrong Zhou (11816537), Jiachen Li (669381), Hui Zhao (7395), Yong Chen (109188), Nicole Stoesser (220513), Guo-Bao Tian (3365051), Lujie Liang (8610960), Wenjing Wei (525144)   +16 more
core   +1 more source

Convergence of Plasmid‐Mediated tmexCD‐toprJ With Critical Resistance Genes Fuels Spread of Multidrug Resistant Bacteria

Advanced Science, EarlyView.
Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song, Meng Wang, Xingyu Wu, Meng Cai, Bowen Li, Qi Wang, Xiaodong Guan, Qi Ding, Ruobing Wang, Hui Wang   +9 more
wiley   +1 more source

Construction and Optimization of Ecological Network in Kuqa, China

Land
The ability to achieve coordinated progress towards ecological protection has become an important ecological network, is the basic guarantee, and an important way to achieve regional and urban ecological security.
Halimulati Abulaiti, Aynur Mamat, Maimaiti Mijiti   +2 more
doaj   +1 more source

Colistin Resistance: Role of swine as reservoir of genes mcr-1, mcr-2, mcr-3, mcr-4 and mcr-5 in intensive production systems in Brazil

, 2021
A distribuição global de genes de resistência à colistina mediada por plasmídeos, como mcr-1, mcr-2, mcr-3, mcr-4 e mcr-5 representa uma preocupação para a saúde pública, uma vez que a colistina é utilizada como a última linha de defesa para o tratamento
Moreira, Jessica
core   +1 more source

A Preclinical Multifunctional Capsule Robot with Unified Diagnosis and Targeted Thermal Therapy for Gastrointestinal Diseases

Advanced Science, EarlyView.
A proof‐of‐concept multifunctional capsule robot integrates diagnostic imaging, magnetic navigation, wireless power transfer, and targeted thermotherapy for gastrointestinal applications. Magnetically guided positioning and stable wireless power enable localized thermal ablation, achieving controlled heating and high cell mortality in vitro.
Heng Zhang, Yichong Sun, Xiaoting Zhang, Chi‐Kwan Lee, Zheng Li, Yehui Li, Huarong Chen, Paul D. Mitcheson   +7 more
wiley   +1 more source

Construction of ecological network in Qujing city based on MSPA and MCR models

Scientific Reports
With the rapid advancement of urbanization and industrialization, ecological patches within cities and towns are fragmented and ecological corridors are cut off, regional ecological security is threatened and sustainable development is hindered. Building
Ji-zheng Qin, Ji-ping Dai, Song-hui Li, Jia-zhen Zhang, Jian-song Peng   +4 more
doaj   +1 more source

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

Advanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao, Zunlei Gong, Chuke Chen, Hui Yu, Yu Cai, Can Liu, Hongkai Huang, Ying Li, Jinyuan Guan, Le Wang, Chengyun Ning, Guoxin Tan, Lei Zhou   +12 more
wiley   +1 more source

Application of MSPA-MCR models to construct ecological security pattern in the basin: A case study of Dawen River basin

Ecological Indicators
Building an ecological security pattern (ESP) can safeguard and improve the structure, functions and services of regional ecosystems. Furthermore, it is also one of the significant spatial methods to mitigate the conflict between ecological conservation ...
Fangyuan Zhang, Yanyan Jia, Xinlong Liu, Tianlu Li, Qingrui Gao   +4 more
doaj   +1 more source

Resistance to Colistin Mediated by mcr-1 among Multidrug Resistant Gram Negative Pathogens at a Tertiary Care Hospital, Egypt

, 2020
Colistin is considered the last option for treatment of infections caused by Multidrug Resistant (MDR) Gram negative pathogens. The mcr-1 gene could transfer the resistance to colistin between different species.
Noha Alaa Eldin Fahim, Nagwa M Abo El Magd, Nagwa M. Abo El Magd, Marwa Shabban, Karim Montasser   +4 more
core   +1 more source