Results 121 to 130 of about 440,166 (303)

Evaluation of antibacterial activity of Pisidium guajava and Gongronema Latifolium [PDF]

, 2008
Pisidium guajava and Gongronema latifolium are local plants used traditionally in south-eastern Nigeria to treat ailments such as cough, loss of appetite, malaria and stomach disorders. In this study, aqueous and ethanolic leaf extracts of P. guajava and
Ajani, O. O., Chinedu, S. N., Nwinyi, O. C.   +2 more
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Minimum inhibitory and bacterial concentrations of theaflavin and synergistic combinations with epicatechin and quercetin against clinical isolates of Stenotrophomonas Maltophilia

, 2012
Stenotrophomonas maltophilia is an important nosocomial pathogen with intrinsic resistance to multiple antibiotics. Previous investigations have shown flavanols from black tea to possess antibacterial activity.
Betts, Jonathan, Haswell, Stephen, Kelly, Stephen, Murphy, Christine   +3 more
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Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Potency of Eucalyptus Oil and Citronella Oil in Suppressing Virulence Factors of Xanthomonas oryzae pv. oryzae

Jurnal Fitopatologi Indonesia
Bacterial leaf blight, caused by the bacterium Xanthomonas oryzae pv. oryzae (Xoo), is an important disease of rice and can cause yield losses of 10-50%.
Alifia Nur Ayusma, Ani Widiastuti, Triwidodo Arwiyanto   +2 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Minimal Inhibitory Concentrations Of Azithromycin In Typhoidal Salmonella Isolated In Tertiary Care Setting

Pakistan Armed Forces Medical Journal
Objective: To determine the variations in minimal inhibitory concentrations (MIC) of Azithromycin amongst Salmonella typhi isolates. Study Design: Cross-sectional study.
Anam Tariq, Irfan Ali Mirza, Qanita Fahim, Ayesha Bashir, Shafqat hussain, Chahat Hussain   +5 more
doaj   +1 more source

Determining the Minimum Inhibitory Concentration of Fulvic Acid on Early Streptococcus mutans Biofilm Formation [PDF]

, 2014
poster abstractFulvic acid is an active ingredient in many homeopathic treatments. Shilajit is one such treatment that is mainly used in the Indian Subcontinent area.
Gregory, Richard L., Tahir, Ali, Witcher, Phillip   +2 more
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Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Anti fungal activity of alcoholic extract of Peganum harmala seeds [PDF]

, 2011
In our study, it was aimed to determine antifungal activity of Peganum harmala on medically important yeasts and molds in vitro. Fungal suspensions of Candida spp and aspergillus spp isolated from the clinical specimens were treated with serial dilutions
Diba, K., Khorshivand, Z., Shabatkhori, M., Shoar, M.G.   +3 more
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