Results 121 to 130 of about 257,516 (311)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Antimicrobial activity of a selection of organic acids, their salts and essential oils against swine enteropathogenic bacteria

Porcine Health Management, 2019
Background Accurate screening of new alternative antimicrobial compounds is essential for their use to control pathogens in swine production due to the replacement of antibiotics and zinc oxide.
Manuel Gómez-García, Cinta Sol, Pedro J. G. de Nova, Mónica Puyalto, Luis Mesas, Héctor Puente, Óscar Mencía-Ares, Rubén Miranda, Héctor Argüello, Pedro Rubio, Ana Carvajal   +10 more
doaj   +1 more source

Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of TP3, TP4, kanamycin, and ampicillin on V. vulnificus.

, 2017
Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of TP3, TP4, kanamycin, and ampicillin on V. vulnificus.
Chieh-Yu Pan (114318), Tsung-Yu Tsai (313172), Bor-Chyuan Su (3639616), Cho-Fat Hui (3133251), Jyh-Yih Chen (114328)   +4 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of rhodanine compounds (μM) against methicillin-resistant Staphylococcus aureus (MRSA).

, 2016
Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of rhodanine compounds (μM) against methicillin-resistant Staphylococcus aureus (MRSA).
Charles R. Ashby Jr (369799), Bhargav A. Patel (3202545), Tanaji T. Talele (223096), Ahmed AbdelKhalek (3202542), Mohamed N. Seleem (680869)   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Raw data for minimum inhibitory concentration (MIC) determination.

Raw data for minimum inhibitory concentration (MIC) determination.
Asfaw Debella (12912244), Zemede Asfaw (8173830), Ermias Lulekal (47970), Bikila Warkineh (11359330), Eyob Debebe (12912247), Mulugeta Alemu (18107158), Sileshi Degu (11261604), Abiy Abebe (8295555)   +7 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Potency of Eucalyptus Oil and Citronella Oil in Suppressing Virulence Factors of Xanthomonas oryzae pv. oryzae

Jurnal Fitopatologi Indonesia
Bacterial leaf blight, caused by the bacterium Xanthomonas oryzae pv. oryzae (Xoo), is an important disease of rice and can cause yield losses of 10-50%.
Alifia Nur Ayusma, Ani Widiastuti, Triwidodo Arwiyanto   +2 more
doaj   +1 more source

Minimum Inhibitory Concentration (MIC) and minimum bactericidal concentration (MBC) of rhodanine compounds (μM) against Vancomycin Resistant Staphylococcus aureus (VRSA) strains.

, 2016
Minimum Inhibitory Concentration (MIC) and minimum bactericidal concentration (MBC) of rhodanine compounds (μM) against Vancomycin Resistant Staphylococcus aureus (VRSA) strains.
Charles R. Ashby Jr (369799), Bhargav A. Patel (3202545), Tanaji T. Talele (223096), Ahmed AbdelKhalek (3202542), Mohamed N. Seleem (680869)   +4 more
core   +1 more source