Results 41 to 50 of about 12,527 (214)

Minimum inhibitory concentration distribution in environmental Legionella spp. isolates [PDF]

Journal of Water and Health, 2014
In Greece standard tests are performed in the watering and cooling systems of hotels’ units either as part of the surveillance scheme or following human infection. The purpose of this study was to establish the minimum inhibitory concentration (MIC) distributions of environmental Legionella isolates for six antimicrobials commonly used for the ...
Vassilios, Sandalakis, Dimosthenis, Chochlakis, Ioannis, Goniotakis, Yannis, Tselentis, Anna, Psaroulaki   +4 more
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Statin Concentrations Below the Minimum Inhibitory Concentration Attenuate the Virulence ofRhizopus oryzae [PDF]

Journal of Infectious Diseases, 2016
Mucormycosis is a destructive invasive mold infection afflicting patients with diabetes and hematologic malignancies. Patients with diabetes are often treated with statins, which have been shown to have antifungal properties. We sought to examine the effects of statins on Rhizopus oryzae, a common cause of mucormycosis.Clinical strains of R.
Bellanger, Anne Pauline, Tatara, Alexander M., Shirazi, Fazal, Gebremariam, Teclegiorgis, Albert, Nathaniel D., LEWIS, RUSSEL EDWARD, Ibrahim, Ashraf S., Kontoyiannis, Dimitrios P.   +7 more
openaire   +3 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

The In vitro Study of Antimicrobial Effect of Teucrium polium Extract on Infectious Microorganisms

پزشکی بالینی ابن سینا, 2014
Introduction & Objective: Teucrium polium belonging to Lamiaceae family has been widely used in traditional medicine for treatment of diseases. Regarding the existence of the active biological compounds in this plant, it seems that this plant has ...
Farideh Tabatabaei Yazdi, Behruz Alizadeh Behbahani, Maryam Heidari Sureshjani, Seyyed Ali Mortazavi   +3 more
doaj  

A study of In vitro antifungal susceptibility patterns of dermatophytic fungi at a tertiary care center in Western India

Indian Journal of Dermatology, 2019
Background: Recent years have seen an alarming rise in the prevalence of recalcitrant and relapsing dermatophyte infections in India associated with lack of clinical response to standard antifungal regimens. Aims and Objectives: A study was undertaken to
Shital Poojary, Autar Miskeen, Jimish Bagadia, Saurabh Jaiswal, Priya Uppuluri   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

In vitro bacteriostatic activity of Origanum vulgare, Cymbopogon citratus, and Lippia alba essential oils in cat food bacterial isolates

Semina: Ciências Agrárias, 2019
The pet industry is currently expanding and specializing mainly in the field of domestic felines. Problems related to antimicrobial resistance are frequent, and the use of essential oils (EOs) in animal feed has become a novel treatment strategy.
Monique Catarine Fischer Possamai, Isabela Carvalho dos Santos, Eloísa Schneider Silva, Zilda Cristiani Gazim, José Eduardo Gonçalves, Andréia Assunção Soares, Ricardo de Melo Germano, Maurício Fanin, Thaís Camaso de Sá, Luciana Kazue Otutumi   +9 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source