Results 51 to 60 of about 440,166 (303)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Effects of UV/H₂O₂ Degradation on the Physicochemical and Antibacterial Properties of Fucoidan

Marine Drugs
The applications of fucoidan in the food industry were limited due to its high molecular weight and low solubility. Moderate degradation was required to depolymerize fucoidan. A few studies have reported that fucoidan has potential antibacterial activity,
Zhicheng He, Biyang Zhu, Lijuan Deng, Lijun You   +3 more
doaj   +1 more source

A study of In vitro antifungal susceptibility patterns of dermatophytic fungi at a tertiary care center in Western India

Indian Journal of Dermatology, 2019
Background: Recent years have seen an alarming rise in the prevalence of recalcitrant and relapsing dermatophyte infections in India associated with lack of clinical response to standard antifungal regimens. Aims and Objectives: A study was undertaken to
Shital Poojary, Autar Miskeen, Jimish Bagadia, Saurabh Jaiswal, Priya Uppuluri   +4 more
doaj   +1 more source

In vitro and in vivo evaluation of cephalosporins for the treatment of Lyme disease. [PDF]

, 2018
BackgroundLyme disease accounts for >90% of all vector-borne disease cases in the United States and affect ~300,000 persons annually in North America.
Ambati, Aditya, Babar, Mustafeez Mujtaba, Inayathullah, Mohammed, Kim, Kwang-Min, Maguire, Peter, Parekh, Mansi B, Pothineni, Venkata Raveendra, Potula, Hari-Hara Sk, Rajadas, Jayakumar, Tayebi, Lobat   +9 more
core  

Novel 1,3-thiazolidin-4-one derivatives as promising anti-Candida agents endowed with anti-oxidant and chelating properties [PDF]

, 2016
Pursuing our recent outcomes regarding the antifungal activity of N-substituted 1,3-thiazolidin-4-ones, we synthesized thirty-six new derivatives introducing aliphatic, cycloaliphatic and heteroaromatic moieties at N1-hydrazine connected with C2 position
Abdurrahman, Aktumsek, Adriano, Mollica, Bizzarri, Bruna, Chimenti, Paola, DE MONTE, Celeste, Emanuela, Mari, Gokhan, Zengin, Rivanera, Daniela, Secci, Daniela, Simone, Carradori, Zicari, Alessandra   +10 more
core   +1 more source

Minimum Inhibitory Concentration (MIC) and minimum bactericidal concentration of beluntas leaf ethanol extract against streptococcus mutans

Journal of Dentomaxillofacial Science, 2022
bjective: The purpose of this study was to determine the exact values of MBC (Minimum Bactericidal Concentration) and MIC (Minimum Inhibitory Concentration) of beluntas leaf extract against Streptococcus mutans colonies. Material and Methood: This study used Streptococcus mutans ATCC 25175 and ethanol extract of beluntas leaves with ...
Elin Septiani, Natallia Pranata, Vinna K. Sugiaman   +2 more
openaire   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

In vitro bacteriostatic activity of Origanum vulgare, Cymbopogon citratus, and Lippia alba essential oils in cat food bacterial isolates

Semina: Ciências Agrárias, 2019
The pet industry is currently expanding and specializing mainly in the field of domestic felines. Problems related to antimicrobial resistance are frequent, and the use of essential oils (EOs) in animal feed has become a novel treatment strategy.
Monique Catarine Fischer Possamai, Isabela Carvalho dos Santos, Eloísa Schneider Silva, Zilda Cristiani Gazim, José Eduardo Gonçalves, Andréia Assunção Soares, Ricardo de Melo Germano, Maurício Fanin, Thaís Camaso de Sá, Luciana Kazue Otutumi   +9 more
doaj   +1 more source