Results 81 to 90 of about 332,055 (262)
Reliability Analysis of Small-Sample Failure Data for Random Truncation High-Voltage Relay
In order to model and evaluate the reliability of long-life high-voltage relays with small-sample fault data characteristics, a reliability analysis method integrating average rank, the minimum mean square distance empirical distribution function, and ...
Yingzhi Zhang +4 more
doaj +1 more source
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Words of Minimum Rank in Deterministic Finite Automata [PDF]
The rank of a word in a deterministic finite automaton is the size of the image of the whole state set under the mapping defined by this word. We study the length of shortest words of minimum rank in several classes of complete deterministic finite automata, namely, strongly connected and Eulerian automata. A conjecture bounding this length is known as
Kari, Jarkko +2 more
openaire +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
On the BIB design having the minimum p-rank
AbstractIt is shown that (i) among BIB designs with parameters (2t+1 − 1, 2t+1 − 1, 2t − 1, 2t − 1, 2t−1 − 1), the incidence matrix of the BIB design PG(t, 2):t − 1 derived from a finite projective geometry PG(t, 2) has the minimum 2-rank and (ii) among BIB designs with parameters (2t, 2t+1 − 2, 2t − 1, 2−1, 2t−1 − 1), the incidence matrix of the BIB ...
N. Hamada, H. Ohmori
openaire +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source

