Results 91 to 100 of about 933,956 (306)

Modelagem agrometeorológica do rendimento de arroz irrigado no Rio Grande do Sul Agrometeorological modelling of irrigated rice yield in Rio Grande do Sul, Brazil

Pesquisa Agropecuária Brasileira, 2008
O objetivo deste trabalho foi elaborar e testar modelos para a estimativa de rendimento de arroz irrigado, no Estado do Rio Grande do Sul. O estudo foi realizado com dados meteorológicos de temperatura mínima do ar, radiação solar global e dados de ...
Eliana Veleda Klering, Denise Cybis Fontana, Moacir Antonio Berlato, Alberto Cargnelutti Filho   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Evaluation of E-waste processing through secondary copper smelting

, 2016
This presentation will report the processing of e-waste and extraction of the valuable metals through secondary copper smelting route (black copper smelting), as shown in Figure 1. The rationale for choosing the selected route will be explained.
Reuter, Markus, Corder, Glen, Ghodrat, Maryam ; https://orcid.org/, Brooks, Geoffrey, Rhamdhani, Muhammad A., Haque, Nawshad, Rhamdhani, Muhammad A, Ghodrat, Maryam (R18544), Glen, Corde, Masood, Syed   +9 more
core   +1 more source

On the Applicability of Temperature and Precipitation Data from CMIP3 for China [PDF]

, 2012
Global Circulation Models (GCMs) contributed to the Intergovernmental Panel on Climate Change (IPCC) Fourth Assessment Report (AR4) and are widely used in global change research.
Alistair G L Borthwick, Qingyun Duan, Duan Qingyun, Miao, Chiyuan, Yang Lin, Miao Chiyuan, Borthwick A. G. L., Duan, Qingyun, Yang L., Borthwick Alistair G. L., Yang, Lin, Borthwick, Alistair G. L., Duan Q. Y., Lin Yang, Miao C. Y., Chiyuan Miao, Alistair G. L. Borthwick   +16 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Ecological features of the flowers of Aesculus hippocastanum L. and characteristics of Aesculus L. pollen seasons under the conditions of central-eastern Poland

Acta Agrobotanica, 2012
The content of Aesculus pollen in aeroplankton of Lublin, located in central-eastern Poland, was studied during the period 2001–2012. The volumetric method was used for the study.
Elżbieta Weryszko-Chmielewska, Maria Tietze, Magdalena Michońska   +2 more
doaj   +1 more source

A 254-nW 20-kHz On-Chip RC Oscillator With 21-ppm/°C Minimum Temperature Stability and 10-ppm Long Term Stability. [PDF]

IEEE Trans Circuits Syst I Regul Pap, 2023
Mirchandani N, Shrivastava A.
europepmc   +1 more source