Results 121 to 130 of about 933,956 (306)

Temperature-mortality relationships from the model with no interaction for the period 1980–2015.

, 2018
The dashed lines represent the 95% empirical confidence interval. MMP, minimum mortality percentile; MMT, minimum mortality temperature; RR, relative risk.
Daniel Devolder (5549468), Joan Ballester (5549471), Hicham Achebak (5549474)   +2 more
core   +1 more source

What Is the Rain‐Fed Wheat and Barley Yield Response to Rainfall Distribution Index in a Cold Sub‐Humid Region?

Meteorological Applications
Rain‐fed crop yields are heavily influenced by seasonal rainfall patterns and temperature, particularly during vegetative and reproductive growth stages.
Fatemeh Razzaghi, Nahid Pourabdollah, Ali Reza Sepaskhah   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Abrasive machining with MQSL. [PDF]

, 2011
Grinding and polishing of engineered components are critical aspects of the precision manufacturing of high performance, quality assured products. Elevated process temperatures, however, are a common and for the most part undesirable feature of the ...
Morris, Tom
core  

Monthly minimum upstream temperature (weighted average)

, 2015
Monthly minimum upstream temperature (weighted ...
Sami Domisch (3317064), Walter Jetz (175506), Domisch, Sami, Giuseppe Amatulli (3317067), Jetz, Walter, Amatulli, Giuseppe   +5 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Data on winter daily minimum temperature and heat energy consumption in South Korea. [PDF]

Data Brief, 2020
Kim Y, Lee S.
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Minimum diving temperature models.

, 2015
Generalized linear models showing the effects of shark length (top-left panel), moon phase (top-right panel), diel phase (bottom-left panel) and sex (bottom-right panel) on the minimum diving temperature of juvenile tiger sharks.
André S. Afonso (596276), Fábio H. V. Hazin (596278)   +1 more
core   +1 more source