Results 81 to 90 of about 605,028 (307)

Effectiveness of minimum-variance hedging

open access: yes, 2007
Advanced electronic trading platforms and index exchange-traded funds (ETFs) have an impact on the minimum-variance hedging of stock indexes with futures.
Carol Alexander (4460518)   +3 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Generalized Minimum Variance Control for MDOF Structures under Earthquake Excitation

open access: yesJournal of Control Science and Engineering, 2016
Control of a multi-degree-of-freedom structural system under earthquake excitation is investigated in this paper. The control approach based on the Generalized Minimum Variance (GMV) algorithm is developed and presented.
Lakhdar Guenfaf, Mohamed Azira
doaj   +1 more source

Design and real time implementation of nonlinear minimum variance filter

open access: yes, 2008
In this paper, the design and real time implementation of a Nonlinear Minimum Variance (NMV) estimator is presented using a laboratory based ball and beam system. The real time implementation employs a LabVIEW based tool. The novelty of this work lies in
Grimble, M.J., Naz, Shamser Ali
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Determination of Optimal Portfolio by Calculating Transaction Costs using Genetic Algorithms on the Jakarta Islamic Index

open access: yesJTAM (Jurnal Teori dan Aplikasi Matematika)
The optimal portfolio is a portfolio that can provide maximum returns at the same level of risk. In investing, the term "high return, high risk" is known, meaning that the higher the return, the higher the risk.
Sinta Oktavia Nur Fadhila   +2 more
doaj   +1 more source

Robust variance-constrained H∞ control for stochastic systems with multiplicative noises

open access: yes, 2007
This is the post print version of the article. The official published version can be obtained from the link below - Copyright 2007 Elsevier Ltd.In this paper, the robust variance-constrained H∞ control problem is considered for uncertain stochastic ...
Liu, X   +7 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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