Results 161 to 170 of about 762,553 (199)

Distribution of tandem repeat polymorphism within minisatellite MS621 (D5S110)

Annals of Human Genetics, 1996
SummaryThe minisatellite MS621 (D5S110) is a highly polymorphic tandem repeat locus which maps to the distal region of human chromosome 5p. Major repeat unit variants at D5S110 differ not by base substitutions but by differences in the repetition of an 11 bp sequence motif found within each repeat. The two major classes of repeat unit thus contain two (
Armour, JAL, Crosier, M, Jeffreys, AJ
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Differences and Similarities Between Various Tandem Repeat Sequences: Minisatellites and Microsatellites

Biochimie, 1997
Tandemly repetitive DNA sequences are abundantly interspersed in the genome of practically all eukaryotic species studied. The relative occurrence of one type of repetitive sequence and its location in the genome appear to be species specific. A common property of repetitive sequences within the living world is their ability to give rise to variants ...
M Dutreix
exaly   +3 more sources

PCR‐free digital minisatellite tandem repeat genotyping

ELECTROPHORESIS, 2011
AbstractWe demonstrated a proof‐of‐concept for novel minisatellite tandem repeat typing, called PCR‐free digital VNTR (variable number tandem repeat) typing, which is composed of three steps: a ligation reaction instead of PCR thermal cycling, magnetic bead‐based solid‐phase capture for purification, and an elongated sample stacking microcapillary ...
Chen, Y Chen, Yuchao, Seo, TS SEO, TAE SEOK   +1 more
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Minisatellite-like repeat sequences in the genome of rodent malaria parasites.

Acta Leidensia, 1992
Using minisatellite DNA probes and various Southern blots containing DNA samples from rodent malaria parasites it was shown that minisatellite-like sequences occur in the genome of these Plasmodium species. In contrast to the high copy number as observed in higher eukaryotes, the use of fingerprinting techniques on DNA from these parasites reveals that
A, van Belkum, G, Trommelen, A, Uitterlinden   +2 more
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Minisatellite variant repeat mapping: Application to DNA typing and mutation analysis

1993
Most DNA typing systems assay allele length variation at tandemly repeated loci such as minisatellites and microsatellites. Allele length measurements are approximate, which impedes the use of such loci in forensic analysis and in studies of allelic variability at hypervariable loci.
A J, Jeffreys, D G, Monckton, K, Tamaki, D L, Neil, J A, Armour, A, MacLeod, A, Collick, M, Allen, M, Jobling   +8 more
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Characterization of Novel Minisatellite Repeat Loci in Atlantic Salmon (Salmo salar) and Their Phylogenetic Distribution

Journal of Molecular Evolution, 1998
We present here the sequence and characterization of various minisatellite-like tandem repeat loci isolated from the genome of Atlantic salmon (Salmo salar). Their diversity of sequence and lack of core motifs common to minisatellites of other species suggest the presence of numerous and previously unidentified simple sequence repeat families in this ...
William S Davidson
exaly   +3 more sources

New method to measure minisatellite variant repeat variation in population genetic studies

American Journal of Human Biology, 2002
AbstractThe classical analysis of minisatellite variant repeat (MVR) variation using modular structures is limited by the lack of knowledge of the mutational process involved in the evolution of most of the minisatellites. In this study a new method to measure MVR variation and to calculate genetic distances using MVR codes is proposed.
M, Brión, R, Cao, A, Salas, M V, Lareu, A, Carracedo   +4 more
openaire   +2 more sources

Digital DNA typing at a second hypervariable locus by minisatellite variant repeat mapping

Human Molecular Genetics, 1993
Minisatellite variant repeat unit mapping by PCR (MVR-PCR) assays the interspersion pattern of variant repeat units along minisatellite alleles. Mapping such internal variation in the highly polymorphic minisatellite MS31A (locus D7S21), reveals extreme levels of allelic variability, far in excess of that detectable by allele length analysis.
D L, Neil, A J, Jeffreys
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The Human Factor VII Gene Is Polymorphic Due to Variation in Repeat Copy Number in a Minisatellite

Gene, 1988
The gene coding for human factor VII, a vitamin K-dependent coagulation factor, contains five minisatellite imperfect tandem repeats with monomer element lengths ranging from 14 to 37 bp, and copy numbers ranging from 6 to 52. Three of these repeats are entirely within introns, one is entirely in an untranslated portion of an exon, and one spans an ...
Patrick J O'Hara, Francis J Grant
exaly   +3 more sources

A 33 bp minisatellite repeat upstream of the ‘mutated in colon cancer’ gene at chromosome 5q21

ELECTROPHORESIS, 1998
AbstractWe have found a 33 bp minisatellite repeat in the 5′‐flanking region of the mutated in colon cancer (MCC) gene at chromosome 5q21. Southern blot experiments demonstrated the locus specificity of the repeat. The number of repeat units varied between 5 and 11 with a heterozygosity of 0.56.
P, Bugert, C, Kenck, G, Kovacs
openaire   +2 more sources