Results 151 to 160 of about 762,553 (199)
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Minisatellite Repeat Coding as a Digital Approach to DNA Typing
Nature, 1991Most DNA typing systems used in forensic and legal medicine assay allelic length variation at tandem repetitive DNA regions such as minisatellites. A simple alternative approach that displays patterns of variant repeat units along minisatellite alleles is described here.
Darren G Monckton +2 more
exaly +4 more sources
Nonradioactive Approach to Type DNA by Minisatellite Variant Repeats
, 1994A nonradioactive approach was established to type DNA by minisatellite variant repeats (MVR). Sequence variation in the repeat units of rninisatellites were described by Jeffreys et al. 1990. The human minisatellite clone MS32 detects the hypervariable locus D1S8. The core sequence of this minisatellite is a 29 bp repeat unit. Approximately half of the
A. Hinney +5 more
semanticscholar +2 more sources
Human Minisatellites, Repeat DNA Instability and Meiotic Recombination
Electrophoresis, 1999Minisatellites include some of the most variable loci in the human genome and are superb for dissecting processes of tandem repeat DNA instability. Single DNA molecule analysis has revealed different mutation processes operating in the soma and germline. Low-level somatic instability results in simple intra-allelic rearrangements.
Yuri Dubrova, Celia A May, Rita Neumann
exaly +3 more sources
Repeat Instability at Human Minisatellites Arising From Meiotic Recombination [PDF]
EMBO Journal, 1998 Little is known about the role of meiotic recombination processes such as unequal crossover in driving instability at tandem repeat DNA. Methods have therefore been developed to detect meiotic crossovers within two different GC-rich minisatellite repeat arrays in humans, both in families and in sperm DNA.
Rita Neumann +2 more
exaly +4 more sources
GATA tandem repeats detect minisatellite regions in blowfly DNA (Diptera: Calliphoridae)
Chromosoma, 2004A DNA probe containing GATA tandem repeats detected numerous dispersed minisatellite regions in the genomes of the blowflies Chrysomya rufifacies and Calliphora erythrocephala. These regions seemed to be actively transcribed into poly(A)+ RNA in a tissue-specific manner.
C. Kirchhoff
semanticscholar +3 more sources
A new minisatellite VNTR marker, Pscp1, discovered for the identification of opium poppy.
Forensic Science International: Genetics, 2021Opium poppy, a member of the Papaveraceae family, is an ancient herbaceous plant and well-known medical resource in the pharmaceutical industry. However, opium poppies are grown worldwide for producing illicit drugs, significantly increasing the ...
Miwha Chang +5 more
semanticscholar +1 more source
MNS16A tandem repeat minisatellite of human telomerase gene and prostate cancer susceptibility. [PDF]
Mutagenesis, 2013 Telomere dysfunction is an early event in the development of prostate cancer and telomerase (TERT) activity is detectable in the majority of prostate cancers. Genetic variation in TERT and its regulatory elements may influence prostate carcinogenesis.
P. Hofer +7 more
semanticscholar +3 more sources
Current Genetics, 2001
We describe the occurrence of a tandem repeat in the chloroplast genome of the marsh orchid, Orchis palustris. The repeat unit is an AT-rich, 16-bp sequence located in the chloroplast tRNALEU intron. Southern blot analysis confirmed that the O. palustris tRNALEU intron including the minisatellite locus has not been transferred to the nucleus, but is ...
Alex Widmer +2 more
exaly +6 more sources
We describe the occurrence of a tandem repeat in the chloroplast genome of the marsh orchid, Orchis palustris. The repeat unit is an AT-rich, 16-bp sequence located in the chloroplast tRNALEU intron. Southern blot analysis confirmed that the O. palustris tRNALEU intron including the minisatellite locus has not been transferred to the nucleus, but is ...
Alex Widmer +2 more
exaly +6 more sources
Minisatellite variant repeat (MVR) mapping: analysis of ‘null’ repeat units at D1S8
Human Molecular Genetics, 1992Minisatellite variant repeat mapping by PCR (MVR-PCR) is a new approach to studying variation in human DNA which analyses interspersion patterns of variant repeats within minisatellite arrays. MVR-PCR has been applied to the hypervariable human minisatellite D1S8 which contains two major classes of variant 29bp repeat units designated a-type and t-type.
K, Tamaki +5 more
openaire +3 more sources
Minisatellite variant repeat (MVR) analysis of the HRAS1 minisatellite locus
ELECTROPHORESIS, 1998AbstractTwo alternative electrophoretic strategies were used to study the internal variation of the HRAS1 minisatellite after minisatellite variant repeat mapping (MVR‐PCR) was carried out. While the use of automated sequencers with fluorescent based technology is ideal for analyzing fragment size, and therefore, for analyzing the repeat number, the ...
A, Vega +3 more
openaire +2 more sources