Results 151 to 160 of about 1,087,727 (251)

Identification of lncRNAs in Breast Cancer Through Bioinformatics Analysis: Implications for Pathogenesis and Prognostic Significance

Cancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Objective Breast cancer (BC) is a disease with a subtle onset, often diagnosed late, and has a high mortality rate. This study aimed to identify long non‐coding RNAs (lncRNAs) linked to BC as prognostic markers using bioinformatics and initial experiments, explore their regulatory pathways, and assess their expression and prognostic ...
Yuhan Zheng, Xinggui Chen, Xuan Liu, Yijin Zhou, Pei Yang, Shuhui Li   +5 more
wiley   +1 more source

Virtual single‐cell perturbation and genetic causal inference reveal CSF1R‐dependent immunometabolic communication in iron metabolism‐associated osteoarthritis

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Integrative genetic, single‐cell, and perturbation analyses identify CSF1R as a macrophage‐centered immunometabolic signaling hub linking iron dysregulation to osteoarthritis. CSF1R‐driven monocyte–macrophage remodeling may coordinate immune activation, extracellular matrix remodeling, and cartilage degeneration, providing a potential therapeutic ...
Yue Zhou, Guohang Shen, Lijing Si, Kaiyong Wang, Yang Chen, Ruoyan Wang, Yupei Dai   +6 more
wiley   +1 more source

Manufacturing cost analysis and exploratory economic evaluation of natural killer cell immunotherapy for paediatric solid tumors

Clinical &Translational Immunology, Volume 15, Issue 9, 2026.
Exploratory economic evaluation of allogeneic NK‐cell therapy for paediatric solid tumors, highlighting treatment costs and the clinical benefit required for cost‐effectiveness. Figure made in ©BioRender—biorender.com. Abstract Objectives Natural killer (NK) cell therapy is a promising allogeneic, off‐the‐shelf immunotherapy for solid tumors, yet ...
Sabera Tabassum Wahid, Melissa Elliott, Yufan Wang, Wayne Nicholls, Natacha Omer, Fernando Souza‐Fonseca‐Guimaraes, Haitham Tuffaha   +6 more
wiley   +1 more source

Cutting Edge: Roles for Batf3-Dependent APCs in the Rejection of Minor Histocompatibility Antigen-Mismatched Grafts. [PDF]

J Immunol, 2015
Atif SM, Nelsen MK, Gibbings SL, Desch AN, Kedl RM, Gill RG, Marrack P, Murphy KM, Grazia TJ, Henson PM, Jakubzick CV.   +10 more
europepmc   +1 more source

Multiomics analyses revealed the roles of the epithelial–mesenchymal transition and novel early candidate diagnostic biomarkers in neonatal necrotising enterocolitis

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
In infants with necrotising enterocolitis (NEC), excessive inflammation and epithelial cell death promote the epithelial–mesenchymal transition (EMT), leading to damage to intestinal barriers and the translocation of bacteria and toxins. In addition, inflamed epithelia release cytokines to strengthen the inflammatory response.
Xiao‐Chen Liu, Guo‐Bin Liu, Chen Cheng, Jin Zhu, Fei‐Fan Chen, Ying Ji, Yu‐Ni Zhang, Xiao‐Lin Yan, Qing Wang, Xin‐Yu Li, Qing Ai, Yuan Shi, Yu He   +12 more
wiley   +1 more source

Development of a Minor Histocompatibility Antigen Vaccine Regimen in the Canine Model of Hematopoietic Cell Transplantation. [PDF]

Transplantation, 2015
Rosinski SL, Stone B, Graves SS, Fuller DH, De Rosa SC, Spies GA, Mize GJ, Fuller JT, Storb R.   +8 more
europepmc   +1 more source

Spatiotemporal immune heterogeneity and precision immunotherapy for ovarian cancer

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Graphical Highlights Spatiotemporal immune heterogeneity shapes distinct and evolving immune ecosystems in ovarian cancer. Multimodal biomarkers enable biologically informed patient stratification beyond static single‐marker approaches. Precision immunotherapy should match dominant immune barriers across lesions and treatment stages.
Xinfeng Yang, Yida Wang, Haiyue You, Jingyi Gao, Yangkun Feng, Feng Zhang, Yan Zhang, Bing Zhang, Shaojie Zhao, Yanfang Gu   +9 more
wiley   +1 more source

Integrated whole genome and transcriptome analysis identified a therapeutic minor histocompatibility antigen encoded by an alternative ITGB2 transcript [PDF]

J Immunother Cancer, 2015
Pont M, van der Lee D, van der Meijden E, van Bergen C, Kester M, Honders M, Vermaat M, Eefting M, Marijt E, Kielbasa S, 't Hoen P, Falkenburg F, Griffioen M.   +12 more
europepmc   +1 more source

B Lymphocytes in Latent Autoimmune Diabetes in Adults: From Autoimmune Activation to Immunometabolic Heterogeneity and Precision Therapeutic Perspectives

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Latent autoimmune diabetes in adults (LADA) is a heterogeneous form of autoimmune diabetes characterised by adult onset, the presence of islet autoantibodies, and a slower progression to insulin dependence compared with classical type 1 diabetes.
Moncef Zouali
wiley   +1 more source

Selection and Characterisation of Minor Histocompatibility Antigen-Specific Regulatory T Cells in Fully HLA-Matched Setting for GVHD Therapy. [PDF]

Eur J Immunol
Pacini CP, Azevedo RI, Ramalhete L, Lainé HAJ, Soares MVD, Lacerda JF.   +5 more
europepmc   +1 more source