Results 171 to 180 of about 30,121 (265)

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

eFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie, Wei Fang, Zean Song, Zhang Yu, Ying Zhu, Shaoping Liu   +5 more
wiley   +1 more source

Spatial and Phenotypic Heterogeneity of ILC Subsets in Mouse Lung Under Type 2 Inflammatory Conditions

European Journal of Immunology, Volume 56, Issue 6, June 2026.
Using cyclic multiplex microscopy in an IL‐33‐driven type 2 inflammation model, we validated a spatial workflow mapping rare lung ILCs. High‐dimensional analysis revealed a conserved peri‐lymphatic niche at early time points of inflammation where ILC2s and myeloid cells co‐localize with LYVE1+ vessels, highlighting a structured immunological ...
Sandy Kroh, Anna Pascual‐Reguant, Artür Manukyan, Ralf Uecker, Robert Günther, Lars Philipsen, Ralf Koehler, Peggy Mex, Markus Landthaler, Raluca A. Niesner, Anja E. Hauser   +10 more
wiley   +1 more source

Maternal CD4⁺ and CD8⁺ T cell tolerance towards a fetal minor histocompatibility antigen in T cell receptor transgenic mice. [PDF]

Biol Reprod, 2013
Perchellet AL, Jasti S, Petroff MG.
europepmc   +1 more source

Induction of Humoral and Cellular Immunity After SARS‐CoV‐2 JN.1 Vaccination in Individuals With and Without Prior Infection

European Journal of Immunology, Volume 56, Issue 6, June 2026.
JN.1 vaccination induced strong, cross‐reactive CD4 and CD8 T‐cell responses and markedly boosted neutralizing antibodies, especially against omicron variants. Influenza vaccine coadministration did not impair immunogenicity. Prior SARS‐CoV‐2 infection was associated with higher baseline and postvaccine neutralizing activity, while cellular responses ...
Caroline Diener, Rebecca Urschel, Saskia Bronder, Candida Guckelmus, Johannes Eckel, Franziska Hielscher, Denisa Bojkova, Sandra Ciesek, Marek Widera, Tina Schmidt, Martina Sester   +10 more
wiley   +1 more source

Dissecting the polygenic architecture of psychopathology via singular value decomposition of eight psychiatric genome‐wide association studies and evaluation of component‐based polygenic scores

General Psychiatry, Volume 39, Issue 3, June 2026.
ABSTRACT Background Current research suggests that genetic risk for psychiatric disorders is largely due to distinct combinations of many common variants shared by different disorders. This points to the existence of latent components affecting different dimensions of psychopathology.
Fernando Facal, Ana M. Pérez‐Gutiérrez, Javier Costas   +2 more
wiley   +1 more source

Efficacy of Multimodal Work‐Up of Head and Neck Squamous Cell Carcinoma Lymph Node Metastasis of Unknown Primary

Head &Neck, Volume 48, Issue 6, Page 1426-1436, June 2026.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) often presents with cervical lymph node metastasis, with 1%–4% of cases presenting as cancer of unknown primary (CUP). CUP poses diagnostic and therapeutic challenges and is linked to poorer survival outcomes.
Robin W. Jansen, Roland M. Martens, Obaida Abdulrahman, Laura Peferoen, C. René Leemans, Gerben J. C. Zwezerijnen, Jan‐Jaap Hendrickx, Pim de Graaf   +7 more
wiley   +1 more source

Characterization of CTL Clones Specific for Single Antigen, H60 Minor Histocompatibility Antigen. [PDF]

Immune Netw, 2011
Jeon JY, Jung KM, Chang J, Choi EY.
europepmc   +1 more source

Human Papillomavirus: Update in Bridging Basic Science to Clinical and Public Health Innovations

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Human papillomavirus (HPV), a non‐enveloped, double‐strand DNA viral pathogen, is intricately linked with the onset of various cancers, including cervical cancer and head and neck cancers. The present paper delves into HPV's ancient recognition and significant milestones such as the discovery of its role in oncogenesis and the development of ...
Fatemeh Beygnejad, Narges Eslami, Kaveh Gharaei Nejad, Atefeh Zamani Kermanshahi, Hossein Bannazadeh Baghi   +4 more
wiley   +1 more source

siRNA silencing of PD-1 ligands on dendritic cell vaccines boosts the expansion of minor histocompatibility antigen-specific CD8(+) T cells in NOD/SCID/IL2Rg(null) mice. [PDF]

Cancer Immunol Immunother, 2015
van der Waart AB, Fredrix H, van der Voort R, Schaap N, Hobo W, Dolstra H.   +5 more
europepmc   +1 more source

Organoids: From Bench to Bedside Applications

MedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li, Rui Cao, Maochen Li, Zichao Tian, Huahao Fan, Bixia Hong, Xiaojuan Liu   +6 more
wiley   +1 more source