Results 91 to 100 of about 344 (255)

Disjoint complete minors and bipartite minors

open access: yesEuropean Journal of Combinatorics, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

On matroid minors that guarantee their duals as minors

open access: yesAdvances in Applied Mathematics, 2015
A natural question for matroids follows: Which matroids N guarantee that, when present as minors in a larger matroid M, their duals are present as minors? The main results of this paper focus on this question with the additional constraint that N and M are 3-connected. We also solve the problem with other connectivity and representability constraints.
openaire   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Northwestern Croatia in the Late Roman Period

open access: yesArheološki Vestnik, 1997
V članku avtor predstavlja arheološko problematiko na območju, ki je v večjem delu pripadalo provinci Saviji. Analizira čas začetka velike krize po smrti cesarjev Valentinijana in Valensa, ko so se tu začeli nepovratni procesi zatona antike, za razliko ...
Vladimir Sokol
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Minority within Minorities

open access: yes
The chapter is a contribution towards the discourse on gender and power in the context of Nambya women in Hwange district in Zimbabwe, who have suffered from multiple marginalisation due to their cultural practices, ethnicity and gender. Of significance are the cultural practices embedded in marriage, ritual practices and family dynamics which are ...
openaire   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

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