Results 91 to 100 of about 2,068 (297)
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Collezione di tavole a supporto del vol. 1° dell\u27opera in 2 volumi "Geographi Græci minores, e codicibus recognovit, prolegomenis annotatione indicibus instruxit, tabulis æri incisis illustravit Carolus Müllerus".
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Dieter Simon, Fontes Minores, II
, 1979 Darrouzès Jean. Dieter Simon, Fontes Minores, II. In: Revue des études byzantines, tome 37, 1979. pp.
Darrouzès, Jean
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Commentaria In Dvodecim Prophetas Minores
KupfertitelEnthalten in: Commentaria In Dvodecim Prophetas Minores, Antwerpen 1661Signatur: III ...
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Pseudo-Quintilianus, Declamationes minores, 250: Sortitio ignominiosorum
, 2016 his essay offers a revised text, the rst Italian translation and a detailed commentary of Pseudo-Quintilian, Declamationes minores, 250: sortitio ...
Dimatteo, Giuseppe, Giuseppe Dimatteo
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Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
698. Annales Juvavenses minores
, 1901 698. Annales Juvavenses minores. In: Molinier Auguste. Les Sources de l'histoire de France - Des origines aux guerres d'Italie (1494). I. Époque primitive, mérovingiens et carolingiens. Paris : A. Picard et fils, 1901.
Molinier, Auguste
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Nebrija y Maquiavelo ante un epigrama de Ausonio: paratexto y texto
Cuadernos de Filología Italiana, 2007 This article analyses the presence of an epigram by the poet Ausonio (IV AD) in Nebrija and in Machiavelli. The text by Ausonio, which in turn derived from a Greek text by Posidipo (III BC), must have been familiar to the European Humanism, since it ...
Cristina Barbolani
doaj
Disjoint complete minors and bipartite minors
European Journal of Combinatorics, 2007 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source