Results 81 to 90 of about 344 (255)
By the end of the twelfth century the bishopric of Wrocław owned a lot of goods and become a major economic power, although it was not sovereign against princely power. On the lands, which were granted to the Bishop, were goods belonging to the prince or
Norbert Jerzak
doaj +1 more source
The role of parental health beliefs in seeking an eye examination for their child. [PDF]
Masarwa D +3 more
europepmc +1 more source
Published as part of Buldrini, Fabrizio, Gentilini, Matteo, Bruni, Cinzia, Santini, Claudio, Alessandrini, Alessandro & Bosi, Giovanna, 2020, Flora vascolare spontanea della città di Modena: analisi del centro storico, pp. 3-56 in Natural History Sciences 7 (1) on page 30, DOI: 10.4081/nhs.2020.443, http://zenodo.org/record ...
Buldrini, Fabrizio +5 more
openaire +2 more sources
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Objective To explore the early diagnosis and the therapy of Sjogren's syndrome combined with hypokalemic periodic paralysis. Methods Clinical data of 2 cases with Sjogren's syndrome and hypokalemic periodic paralysis were analyzed.
Xiao⁃juan CHENG +2 more
doaj
[Bilateral vocal cord paralysis with acute airway obstruction and urgent tracheotomy in a patient with an acute vertebrobasilar stroke]. [PDF]
Díaz-Pérez C +4 more
europepmc +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Nebrija y Maquiavelo ante un epigrama de Ausonio: paratexto y texto
This article analyses the presence of an epigram by the poet Ausonio (IV AD) in Nebrija and in Machiavelli. The text by Ausonio, which in turn derived from a Greek text by Posidipo (III BC), must have been familiar to the European Humanism, since it ...
Cristina Barbolani
doaj

