Results 51 to 60 of about 1,723 (300)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
DORĘCZENIA PISM PROCESOWYCH (UWAGI NA MARGINESIE CTH. 2,4,1 [A. 318/319] = C. 5,4,20)
Zeszyty Prawnicze, 2016 THE NATURAL SCIENCES IN THE SERVICE OF PLEADINGS IN CASES INVOLVING MINORS: REMARKS ON CTH 2.4.1 [A. 318/319] = C. 5.4.20) Summary The subject of this article is the status of juvenile persons in Roman law, as exemplified by one of the constitutions ...
Jacek Wiewiorowski
doaj +1 more source
Patres conscripti (e minores gentes)
, 1989 Domenico Musti, Patres conscripti (e minores gentes), p. 207-227. L'equazione tra patres minorum gentium e conscripti, talora ammessa, viene altre volte respinta perché non vi sarebbe una chiara testimonianza : il passo di Dionisio, II 47, 1 è stato ...
Domenico Musti, Musti, Domenico
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Dieter Simon, Fontes Minores, IV
, 1982 Failler Albert. Dieter Simon, Fontes Minores, IV. In: Revue des études byzantines, tome 40, 1982. pp.
Failler, Albert
core +1 more source
The excluded minors for the class of spike minors
Advances in Applied Mathematics25 pages, 5 ...
Sam Bastida +6 more
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
"Bonshommes”, (the “new people”) and the pre-communal “conspiracy”. XI-XII Centuries
Montesquieu.it, 2018 In the crisis of the ancient political and ecclesiastical orders, which represented a true crisis in the legitimacy of the traditional authorities (Regnum e Sacerdotium fighting for universal supremacy), a profound and dramatic crisis for the medieval ...
Rita Bellelli
doaj +1 more source