Results 51 to 60 of about 196,839 (313)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Young and Restless

open access: yesS: I. M. O. N.
Based on testimonies from the Fortunoff Video Archive and other personal accounts, this article delves into the political options and the mechanisms of political mobilisation among Jewish youngsters in 1930s and 1940s Romania.
Anca Filipovici
doaj   +1 more source

Political Representation of National Minorities: A Case Study of Minority Parties in Serbia [PDF]

open access: yes, 2013
This thesis explores the relationship between descriptive and substantive representation of national minorities. Previous studies have emphasized the importance of descriptive representation and justified the need for affirmative action measures such as ...
Loncar, Jelena
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Minorities in Yemen Reality and Challenges [PDF]

open access: yes, 2020
Yemen is home to religious and sectarian minorities who represent about 0.5% of the total population. In addition to Muslims, there is a minority of Jews, who’s presence has drastically shrunk over the years due to the multiple violations and ...
Almahfali, Mohammed, Homaid, Eman
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Using Baidu Index to Understand the Public Concern of Children's Mental Health in Mainland China in the Context of COVID-19 Epidemic

open access: yesJournal of Education, Health and Sport, 2022
This study aims to understand the temporal and spatial characteristics of public concern for "children's mental health" in China in the context of the COVID-19 epidemic.
Qinyi Tan, Fang He, Luyan Teng
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Cultural preservation through ICT amongst ethnic minorities in Malaysia [PDF]

open access: yes, 2021
Information and Communication Technology (ICT) has gradually evolved into a necessity for all members of society, whether in urban or rural areas. As ICT has penetrated almost every aspect of human daily lives, its impact on the culture and identity of ...
Choo, Yeong Khong   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy