Results 71 to 80 of about 743,702 (309)

Reviewing the Problems in Rural Teacher Policy Instrumentsand Optimization Strategies: Based on the Analysis Framework of McDonnel and Elmore

open access: yesJiaoshi jiaoyu xuebao
As a comprehensive education and livelihood project, the construction of the rural teacher workforce is an important aspect of promoting the strategy of rural revitalization and deepening educational reform.
CHEN Hui, LI Chencheng
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Exclusion of women and vulnerable minorities [PDF]

open access: yes, 2019
Women and various groups of vulnerable minorities (i.e. indigenous peoples) are major stakeholders in food systems. They are under-represented in decision-making bodies and are not properly considered in various policies and interventions.
Dury, Sandrine, Sirdey, Ninon
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Declining returns of secondary vocational education on subjective class identity across generations and time periods

open access: yesHumanities & Social Sciences Communications
This study explores the association of secondary vocational education (SVE) on subjective class identification in China, focusing on comparisons with compulsory and academic high school education, and analyzing regional and historical variations.
Penghui Wu, Ming Zhang, Demei Yang
doaj   +1 more source

Poverty, Minorities, and Respect for Law [PDF]

open access: yes, 1970
Students spend most of their waking hours with their teachers and peers, who are considered to be the significant others, that influence their learning motivation and school life.
Wright, J. Skelly
core   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Integrating Traditional Ecological Knowledge into Land Use and Land Cover Change Assessments, Pastoralist Communities in Northwest Inner Mongolia China

open access: yesLand
Land use and land cover (LULC) changes are the primary drivers of ecosystem transformation and have substantial impacts on local livelihoods. However, most research has focused on assessing the intensity of these changes in specific regions using ...
Siru A   +3 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Fairness perceptions of video resumes among ethnically diverse applicants [PDF]

open access: yes, 2012
This study investigated ethnic majority and minority applicants’ fairness perceptions (n = 445) of video resumes, compared to paper resumes. Additionally, the moderating effect of minorities’ ethnic identity and language proficiency on fairness ...
Born, Marise Ph   +3 more
core   +1 more source

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