Results 61 to 70 of about 115,232 (269)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Rachel Humphris. 2019. Home-Land: Romanian Roma, Domestic Spaces and the State. Bristol: Bristol University Press, 240 p.

Martor, 2020
This volume by Rachel Humphris investigates the most intimate spheres of the social interaction with the street level bureaucracy of the state. The main actors involved in the interactions described and analyzed are the street level social “frontline ...
László Fosztó
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Reviewing the Problems in Rural Teacher Policy Instrumentsand Optimization Strategies: Based on the Analysis Framework of McDonnel and Elmore

Jiaoshi jiaoyu xuebao
As a comprehensive education and livelihood project, the construction of the rural teacher workforce is an important aspect of promoting the strategy of rural revitalization and deepening educational reform.
CHEN Hui, LI Chencheng
doaj   +1 more source

The excluded minors for the class of spike minors

Advances in Applied Mathematics
25 pages, 5 ...
Sam Bastida, Nick Brettell, Rutger Campbell, George Drummond, Emma Hogan, Charles Semple, Gerry Toft   +6 more
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Declining returns of secondary vocational education on subjective class identity across generations and time periods

Humanities & Social Sciences Communications
This study explores the association of secondary vocational education (SVE) on subjective class identification in China, focusing on comparisons with compulsory and academic high school education, and analyzing regional and historical variations.
Penghui Wu, Ming Zhang, Demei Yang
doaj   +1 more source

Integrating Traditional Ecological Knowledge into Land Use and Land Cover Change Assessments, Pastoralist Communities in Northwest Inner Mongolia China

Land
Land use and land cover (LULC) changes are the primary drivers of ecosystem transformation and have substantial impacts on local livelihoods. However, most research has focused on assessing the intensity of these changes in specific regions using ...
Siru A, Bingxue Xie, Menghe Wuliji, Lisheng Zhao   +3 more
doaj   +1 more source