Results 61 to 70 of about 249,361 (251)
BMC PsychologyPurpose This study investigates the impact of internet use on the subjective well-being of Chinese rural residents, with a focus on the mediating role of cultural consumption.
Penghui Wu +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Jiaoshi jiaoyu xuebaoThe reform of educational evaluation in the new era means that educational evaluation has entered a new stage of development, which will demonstrate extraordinary value and strategic significance in politics, history, and reality. Understanding what kind
ZHU Dequan, CAO Dufan
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Religious minorities in Ukraine: current issues
, 2022 The article presents the results of a sociological study on the main issues relevant to religious minorities in modern Ukraine. The main ones are legal aspects related to legislation, state registration, acquiring the status of a legal entity, obtaining ...
Pyvovarova N. P. +7 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Frontiers in Psychology, 2019 The minorities in Southwest China are characterized by a blend of diverse cultures. It is not clear how values predict behaviors in such a population.
Yanli Yang +8 more
doaj +1 more source
Minorities in Yemen Reality and Challenges [PDF]
, 2020 Yemen is home to religious and sectarian minorities who represent about 0.5% of the total population. In addition to Muslims, there is a minority of Jews, who’s presence has drastically shrunk over the years due to the multiple violations and ...
Almahfali, Mohammed, Homaid, Eman
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source