Results 101 to 110 of about 909,888 (305)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

CLOSING THE MINORITY PRESCRIPTION DRUG GAP

, 2005
ANCHOR LEAD: A new Medicare prescription drug benefit coming in 2006 will lend a helping hand to minorities in need. Jon McNally has more. (:60) SCRIPT: Healthcare Now, I’m Jon McNally.

core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

April is Minority Health Month 2011 [PDF]

CDC\u2019s Office of Minority Health and Health Equity invites you to celebrate Minority Health Month by exploring the evolution of minority health in the United States ...

core   +1 more source

Clinical and sociodemographic characteristics associated with health-related quality of life among older breast cancer survivors

Women's Health
Background: Health-related quality of life (HRQoL) measures may help incorporate patient preferences and deliver individualized care for older breast cancer survivors.
Jacob Schneider, Kaitlyn M. Wojcik, Emma Tian, Oliver W. A. Wilson, Jinani Jayasekera   +4 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

The Relationship Between Personality Characteristics and Acceptance of Minority Influence [PDF]

, 2011
According to the literature on social influence, there is a strong relationship between exposure to minority points of view and divergent thinking (i.e., thinking characterized as fluid, flexible, and more creative).
Nicholls, Ryan M.
core  

Disjoint complete minors and bipartite minors

European Journal of Combinatorics, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Minority Advisory Committee Memo re: Meeting with UNITY Students

, 1985
One page memo dated February 6, 1985 from Ramón Chacón, then SCU faculty member and Chair of the Minority Advisory Committee, to Robert M. Senkewicz, S.J., then Vice President of Student Services, in response to Senkewicz's memo of February 4.
Chacón, Ramón D. (Ramón David);
core   +1 more source