Results 81 to 90 of about 743,854 (316)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Toward an understanding of sexual minority women’s social stressors and health in post-communist countries in Europe: a scoping review

BMC Public Health
Background While significant evidence demonstrates disproportionate burden of poor health among sexual minority men and transgender women, there is a dearth of research on the health of sexual minority women (SMW). We conducted a review to examine social
Lauren Bochicchio, Tonda L. Hughes, Zamfira Parincu, Elizabeth Chadbourne, Corina Lelutiu-Weinberger   +4 more
doaj   +1 more source

The excluded minors for the class of spike minors

Advances in Applied Mathematics
25 pages, 5 ...
Sam Bastida, Nick Brettell, Rutger Campbell, George Drummond, Emma Hogan, Charles Semple, Gerry Toft   +6 more
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Minority carrier lifetime mapping of solar cells [PDF]

, 2011
The minority carrier lifetime distribution across silicon solar cells was investigated using variations of the open circuit voltage decay method. This was performed on monocrystalline, polycrystalline and amorphous silicon solar cells. Light from a white
Fisher, Rebbeca
core   +1 more source

Introduction to Special Issue “Marginality on the Margins of Europe – The Impact of COVID-19 on Roma Communities in Non-EU Countries in Eastern Europe”

Journal on Ethnopolitics and Minority Issues in Europe, 2022
Andreea Cârstocea, Craig Willis
doaj   +1 more source

Research Progress in the Medicine-Food Dual Use of in Digestive System Tumors

Natural Product Communications
Angelica sinensis (AS) is a widely used medicinal and culinary herb frequently considered critical in traditional prescriptions. Modern pharmacological studies have validated its beneficial effects, including nourishing, blood activation, anti ...
Taiqiang Jiao, Xiangyang Li, Wengjie Jiang, Yifan Yang, Jiaqing Li, Yang Niu, Yi Nan   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Minority Affairs Committee Endorsement of UNITY Proposal [PDF]

, 1985
One page memo dated May 9, 1985, from Ramón Chacón, then SCU faculty member and Chair of the Minority Advisory Committee, to Robert M. Senkewicz, S.J., then Vice President of Student Services, indicating the Minority Advisory Committee's support of the ...
Senkewicz, Robert M., 1947-; Chacón, Ramón D. (Ramón David);
core