Results 71 to 80 of about 743,854 (316)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

S.C. Commission for Minority Affairs Small and Minority Business Division [PDF]

open access: yes, 2023
The mission of the South Carolina Commission for Minority Affairs Small and Minority Business Division is to identify key issues and services that are necessary for the development of minority, small businesses, as well as the best measures for ...
South Carolina Commission for Minority Affairs
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Mental health symptoms and discrimination among immigrant and US-born Hispanic or Latino adults during the COVID-19 pandemic

open access: yesBMC Psychology
Background Mental health symptoms are highly stigmatized, potentially increasing the risk of experiencing discrimination, particularly within minoritized communities such as Hispanic or Latino populations.
Emmanuel A. Odame   +5 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Maryland Chartbook of Minority Health And Minority Health Disparities Data [PDF]

open access: yes, 2009
The Office of Minority Health and Health Disparities (MHHD) was established in the Maryland Department of Health and Mental Hygiene in 2004 by legislation passed in the Maryland General Assembly session of that same year.

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Prevalence of depressive symptoms among Hispanic/Latino ethnic subgroups during the COVID-19 pandemic

open access: yesScientific Reports
Hispanic/Latino populations experienced disproportionate exposure to depression risk factors during the COVID-19 pandemic. While aggregated data confirm the risks of depressive symptoms among Hispanic/Latino individuals, little research uses ...
Maryam Elhabashy   +5 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Minority Health Month [PDF]

open access: yes, 2008
Quarterly; Vol. 1, issue 1 (summer 2008); v. 13 no. 1 (winter 2008); Jan. 2012-; "A partnership between State Government, the Community and the Private Sector."; First online issue (Summer 2008) is v. 1, no.

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An integrated microbiome-drug interaction and bioinformatics approach identifies active deglycosylated and glycosidic chain metabolites of Platycodin D targeting PTPN2/HIF1A in acute lung injury

open access: yesBiology Direct
Background Platycodin D (PD) is a typical triterpenoid saponin with low oral bioavailability. Despite its potent anti-ALI effects, its active metabolites and underlying mechanisms remain unclear, thereby significantly impeding its further development ...
Yuanhan Zhong   +11 more
doaj   +1 more source

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