Results 71 to 80 of about 29,267 (217)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Analyzing risk factors for second malignancies in early gastric carcinoma from the SEER database

open access: yesScientific Reports
This retrospective study analyzed a large population of gastric cancer (GC) patients treated between 2010 and 2015 to investigate the clinical features and predictive risk factors for developing secondary primary malignancies (SPMs).
Lei Song   +6 more
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Clinical and sociodemographic characteristics associated with health-related quality of life among older breast cancer survivors

open access: yesWomen's Health
Background: Health-related quality of life (HRQoL) measures may help incorporate patient preferences and deliver individualized care for older breast cancer survivors.
Jacob Schneider   +4 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Music without Borders:

open access: yesMuzikološki Zbornik, 2019
This article presents some of the results of a re­search project which the author conducted between 2015 and 2018. The influences of the music lessons which were offered within the framework of this research project is the main subject of this article ...
Hande Saglam
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Culture defence a polskie prawo karne

open access: yesArchiwum Kryminologii, 2008
Tekst porusza problem stosowania się do prawa krajowego państwa goszczącego mniejszości wywodzących się z różnych kręgów kulturowych. Autorka artykułu przygląda się i szczegółowo omawia w tym zakresie zapisy 27 Międzynarodowego paktu praw obywatelskich i
Sitarz Olga
doaj   +1 more source

Minority within Minorities

open access: yes
The chapter is a contribution towards the discourse on gender and power in the context of Nambya women in Hwange district in Zimbabwe, who have suffered from multiple marginalisation due to their cultural practices, ethnicity and gender. Of significance are the cultural practices embedded in marriage, ritual practices and family dynamics which are ...
openaire   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

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