Results 51 to 60 of about 946,179 (307)
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Discriminating language rights and politics in the post-Yugoslav states [PDF]
Pupavac examines the rise of linguistic human rights advocacy and its approach in a case study of language politics in the post-Yugolav states. A core concern of contemporary linguistic rights advocacy has been to tackle ethnically based discrimination ...
Pupavac, Vanessa
core +2 more sources
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Ownership Concentration and Share Valuation: Evidence from Germany. [PDF]
Concentrated ownership of large listed companies is widespread throughout the world, and Germany is typical in this respect. This paper proposes a method of distinguishing empirically between the beneficial and harmful effects of ownership concentration,
Alfons J. Weichenrieder +1 more
core +3 more sources
A growing body of literature provides important insights into the meaning and impact of the right to marry a same-sex partner among sexual minority people.
Laurie A Drabble +7 more
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
[Review of] Georgina Ashworth (Ed.). World Minorities [PDF]
At the present time, World Minorities is a very appropriate title for a book, since it coincides with the thirtieth anniversary of the Universal Declaration of Human Rights and President Jimmy Carter\u27s strong, favorable stand for them. The publication
Husain, Asad
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Background Accessing health rights is an integral component of people’s aspirations for a better life. Existing discussions and evaluations regarding the accessibility of health rights for minority rural migrants are insufficient.
Qingjun Zhao, Guosong Wu, Hanrui Wang
doaj +1 more source

