Results 51 to 60 of about 946,179 (307)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Discriminating language rights and politics in the post-Yugoslav states [PDF]

open access: yes, 2006
Pupavac examines the rise of linguistic human rights advocacy and its approach in a case study of language politics in the post-Yugolav states. A core concern of contemporary linguistic rights advocacy has been to tackle ethnically based discrimination ...
Pupavac, Vanessa
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Ownership Concentration and Share Valuation: Evidence from Germany. [PDF]

open access: yes
Concentrated ownership of large listed companies is widespread throughout the world, and Germany is typical in this respect. This paper proposes a method of distinguishing empirically between the beneficial and harmful effects of ownership concentration,
Alfons J. Weichenrieder   +1 more
core   +3 more sources

Perceived psychosocial impacts of legalized same-sex marriage: A scoping review of sexual minority adults' experiences.

open access: yesPLoS ONE, 2021
A growing body of literature provides important insights into the meaning and impact of the right to marry a same-sex partner among sexual minority people.
Laurie A Drabble   +7 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

[Review of] Georgina Ashworth (Ed.). World Minorities [PDF]

open access: yes, 1979
At the present time, World Minorities is a very appropriate title for a book, since it coincides with the thirtieth anniversary of the Universal Declaration of Human Rights and President Jimmy Carter\u27s strong, favorable stand for them. The publication
Husain, Asad
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Effect of health rights accessibility on the urban integration of minority rural migrants in China: a cross-sectional study

open access: yesBMC Public Health
Background Accessing health rights is an integral component of people’s aspirations for a better life. Existing discussions and evaluations regarding the accessibility of health rights for minority rural migrants are insufficient.
Qingjun Zhao, Guosong Wu, Hanrui Wang
doaj   +1 more source

Home - About - Disclaimer - Privacy