Results 61 to 70 of about 93,366 (309)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Minority consultative bodies in Kosovo: A quest for effective emancipation or elusive participation? [PDF]

open access: yes, 2011
This paper examines the extent to which effective political participation can be achieved through minority consultative bodies, and what obstacles and shortcomings can potentially occur in practice.
Gezim Visoka   +3 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Recognizing religious minority rights: a key tool to managing pluralism in the European Court of Human Rights

open access: yes, 2021
The article examines how the European Court of Human Rights (ECtHR) engages with the rights of religious minorities within the framework of the European Convention on Human Rights (ECHR).
Relaño Pastor, Eugenia
core   +1 more source

Effect of health rights accessibility on the urban integration of minority rural migrants in China: a cross-sectional study

open access: yesBMC Public Health
Background Accessing health rights is an integral component of people’s aspirations for a better life. Existing discussions and evaluations regarding the accessibility of health rights for minority rural migrants are insufficient.
Qingjun Zhao, Guosong Wu, Hanrui Wang
doaj   +1 more source

Religious Diversity and Promotion of Minority Rights, Do They Really Go Hand in Hand?

open access: yesReligions
One might expect the promotion of religious minority rights to be linked to the growth of religious diversity. However, the data in the Atlas of Religious and Belief Minority Rights, on which this article is based, does not support this expectation ...
Silvio Ferrari
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

If Yes, Why Not? Minority Language Use and Accommodation of Minority Language Rights in Slovakia

open access: yesActa Universitatis Sapientiae: European and Regional Studies, 2015
This article gives an overview of the actual situation of language rights in Slovakia, focusing mainly on the minority language usage. The status of minority languages in Slovakia is still a politicized question and a series of conflicts arose especially
Vass Ágnes
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Comment: The Normative Framework of the African Human Rights Regime on the Rights of Minorities

open access: yesMizan Law Review, 2015
Minority issues in Africa have surfaced in various dimensions affecting the socio-political landscape of the continent. The protection of minorities is without doubt crucial to securing sustainable peace, economic development as well as protection and ...
B Dessalegn
doaj   +1 more source

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