Results 81 to 90 of about 93,366 (309)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Breaking the cycle of exclusion : minority rights in Georgia today

open access: yes, 2009
Minority Rights Group ...
Minority Rights Group International
core  

Promovarea eficientă a Declarației ONU cu privire la drepturile persoanelor aparținând minorităților naționale sau etnice, religioase și lingvistice - Raport al Raportorului Special al ONU privind problemele minorităților (ONU, 2020) [PDF]

open access: yesDrepturile Omului, 2020
In the analyzed report, the Special Rapporteur on minority issues, Fernand de Varennes, briefly presents his activities in 2019 and 2020 to the General Assembly, highlighting the continuous work on the thematic priorities of statelessness, education and ...
Adina – Maria Nikolić
doaj  

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Group rights, collective goods, and the problem of cross-border minority protection [PDF]

open access: yes, 2019
This article argues that there are both practical and conceptual reasons for relaxing the prevailing state-centric frameworks for minority protection in the global arena.
Vitikainen, Annamari
core   +1 more source

Democracy and Minority Rights

open access: yesČasopis pro Právní Vědu a Praxi, 1995
The strongest defence of democracy as a juridical-political constellation lies in its openness to pluriformity and its willingness to allow and create possibilities for public rational debate. People with diverging ideas should in principal have a chance
Theo van Dijk
doaj  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Challenging assumptions of the enlargement literature : the impact of the EU on human and minority rights in Macedonia [PDF]

open access: yes, 2011
This article argues that from the very start of the transition process in Macedonia, a fusion of concerns about security and democratisation locked local nationalist elites and international organisations intoa political dynamic that prioritised security
Koinova, M.   +2 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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