miR-132-3p priming enhances the effects of mesenchymal stromal cell-derived exosomes on ameliorating brain ischemic injury [PDF]
Stem Cell Research & Therapy, 2020 Backgrounds/aims Mesenchymal stromal cell-derived exosomes (MSC-EXs) could exert protective effects on recipient cells by transferring the contained microRNAs (miRs), and miR-132-3p is one of angiogenic miRs.
Qunwen Pan +11 more
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miR-132-3p and KLF7 as novel regulators of aortic stiffening-associated EndMT in type 2 diabetes mellitus [PDF]
Diabetology & Metabolic Syndrome, 2023 Background The prevalence of diabetes mellitus has risen considerably and currently affects more than 422 million people worldwide. Cardiovascular diseases including myocardial infarction and heart failure represent the major cause of death in type 2 ...
Melanie S. Hulshoff +10 more
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MTFR2 promotes endometrial carcinoma cell proliferation and growth via the miR-132-3p/PI3K/Akt signaling pathway [PDF]
Frontiers in MedicineObjectiveUnderstanding the mechanisms underlying endometrial cancer progression is crucial for the development of effective targeted therapies. In this study, we investigated the role of MTFR2 in endometrial cancer cell.MethodsThe expression of MTFR2 in ...
Zhijun Niu +7 more
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Exosomal miR-132-3p from mesenchymal stromal cells improves synaptic dysfunction and cognitive decline in vascular dementia [PDF]
Stem Cell Research & Therapy, 2022 Background/aims Vascular dementia (VD) results in cognition and memory deficit. Exosomes and their carried microRNAs (miRs) contribute to the neuroprotective effects of mesenchymal stromal cells, and miR-132-3p plays a key role in neuron plasticity. Here,
Xiaotang Ma +7 more
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Lung cancer-derived exosomal miR-132-3p contributed to interstitial lung disease development [PDF]
World Journal of Surgical Oncology, 2023 Purpose Interstitial lung diseases (ILDs) have high morbidity and mortality and poor prognosis. The significance of microRNAs (miRNAs) was highlighted in ILDs development.
Sufang Fang +5 more
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Circ_DOCK1 regulates USP11 through miR-132-3p to control colorectal cancer progression [PDF]
World Journal of Surgical Oncology, 2021 Background Circular RNAs (circRNAs) take part in colorectal cancer malignancies. CircRNA dedicator of cytokinesis 1 (circ_DOCK1) is involved in colorectal cancer progression, but the mechanism underlying this circRNA that takes part in colorectal cancer ...
Weitong Zhang +3 more
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miR-132-3p downregulates in CD4 T cells and is associated with disease manifestations in patients with lupus [PDF]
Journal of International Medical ResearchObjective This study aimed to evaluate the expression status of miR-132-3p in CD4 + T cells in patients with systemic lupus erythematosus (SLE) and explore its potential role in SLE development.
Haihong Qin +5 more
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MiR-132-3p Modulates MEKK3-Dependent NF-κB and p38/JNK Signaling Pathways to Alleviate Spinal Cord Ischemia-Reperfusion Injury by Hindering M1 Polarization of Macrophages [PDF]
Frontiers in Cell and Developmental Biology, 2021 Spinal cord ischemia-reperfusion (SCIR) injury is a serious complication of open surgical and endovascular aortic procedures. MicroRNA-132-3p (miR-132-3p) has been reported to be involved in the progression of various diseases, but its role in SCIR ...
Hua Fang +17 more
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MiR-132-3p suppresses peritoneal fibrosis induced by peritoneal dialysis via targeting TGF-β1/Smad2/3 signaling pathway. [PDF]
PLoS ONEBackgroundPeritoneal fibrosis (PF) is the main complication of peritoneal dialysis (PD) and the most common cause of cessation from PD. There is still no effective therapeutic approach to reserve PF.
Yangyang Yin +5 more
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circRNF20 aggravates the malignancy of retinoblastoma depending on the regulation of miR-132-3p/PAX6 axis [PDF]
Open Medicine, 2022 Circular RNAs (circRNAs) serve as essential players in diverse human cancers, including retinoblastoma (RB). In this study, the function of circRNA Ring Finger Protein 20 (circRNF20) in RB progression was investigated.
An Dexiang, Yang Jing, Ma Linli
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