THE ROLE OF MICRORNAS (MIRNAs) IN THE REGULATION OF TAU PATHOLOGY [PDF]
, 2020 Tauopathies are a class of sporadic neurodegenerative disorders including Alzheimer’s disease (AD), Pick’s disease, Corticobasal degeneration and Progressive supranuclear palsy, characterized by hyperphosphorylation and aggregation of the microtubule ...
LAURETTI, ELISABETTA
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Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria [PDF]
, 2016 Malaria remains one of the greatest public health challenges worldwide, particularly in sub-Saharan Africa. The clinical outcome of individuals infected with Plasmodium falciparum parasites depends on many factors including host systemic inflammatory ...
A Bhoumik +64 more
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Frontiers in PhysiologyBackgroundCerebral collateral circulation (CCC) considerably improves the prognosis of patients with symptomatic carotid stenosis (SCS). This study evaluated the diagnostic value of plasma microRNAs (miRNAs) in determining CCC status in patients with SCS.
Wenwen Liang +5 more
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, 2014 Osteosarcoma (OS) is the most common primary bone cancer exhibiting high genomic instability. This genomic instability affects multiple genes and microRNAs to a varying extent depending on patient and tumor subtype.
Baumhoer, D. (Daniel) +6 more
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Distinct miRNA signatures associate with subtypes of cholangiocarcinoma from infection with the tumourigenic liver fluke Opisthorchis viverrini [PDF]
, 2014 Background & Aims: Intrahepatic cholangiocarcinoma (ICC) is a significant public health problem in East Asia, where it is strongly associated with chronic infection by the food-borne parasite Opisthorchis viverrini (OV). We report the first comprehensive
Bethony, Jeffrey M. +12 more
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BRAF(V600) inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells [PDF]
, 2019 The BRAF inhibitors vemurafenib and dabrafenib can be used to treat patients with metastatic melanomas harboring BRAF(V600) mutations. Initial antitumoral responses are often seen, but drug-resistant clones with reactivation of the MEK-ERK pathway soon ...
Bagge, Roger Olofsson +10 more
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A Downmodulated MicroRNA Profiling in Patients with Gastric Cancer
Gastroenterology Research and Practice, 2017 Objective. Here, we aim to investigate the microRNA (miR) profiling in human gastric cancer (GC). Methods. Tumoral and matched peritumoral gastric specimens were collected from 12 GC patients who underwent routine surgery.
Tao Zhang +5 more
doaj +1 more source
Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-Viral hsa-miR-132 Processing in CEM-SS Cells [PDF]
Background: Despite tremendous advances in antiretroviral therapy (ART) against HIV-1 infections, no cure or vaccination is available. Therefore, discovering novel therapeutic strategies remains an urgent need.
Aathma Bejoy +11 more
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Investigating circulating miRNAs as predictors of therapeutic response in metastatic castration-resistant prostate cancer [PDF]
, 2019 Metastatic castration-resistant prostate cancer (mCRPC) is advanced prostate cancer (PCa) that has developed resistance to first-line androgen deprivation therapies. For mCRPC, several treatments are available, but the response rate is usually low (
Shibakawa, Akifumi
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, 2020 Abstract Colorectal cancer (CRC) is the most common cause of cancer-related mortality in the world. Long non-coding RNAs (lncRNAs) were involved in the development of many cancers. However, studies on the effect of lncRNA small nucleolar RNA host gene 16 (SNHG16) on the proliferation, metastasis and apoptosis of CRC cells were still few. SNHG16
He,Xiaowen +4 more
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