Results 101 to 110 of about 54,811 (219)

Structuring osteosarcoma knowledge: an osteosarcoma-gene association database based on literature mining and manual annotation

, 2014
Osteosarcoma (OS) is the most common primary bone cancer exhibiting high genomic instability. This genomic instability affects multiple genes and microRNAs to a varying extent depending on patient and tumor subtype.
Baumhoer, D. (Daniel), Korsching, E.U. (Eberhard), Maugg, D. (Doris), Nathrath, M. (Michaela), Neumann, A. (Anna), Poos, K. (Kathrin), Smida, J. (Jan)   +6 more
core   +1 more source

Investigating circulating miRNAs as predictors of therapeutic response in metastatic castration-resistant prostate cancer [PDF]

, 2019
Metastatic castration-resistant prostate cancer (mCRPC) is advanced prostate cancer (PCa) that has developed resistance to first-line androgen deprivation therapies. For mCRPC, several treatments are available, but the response rate is usually low (
Shibakawa, Akifumi
core   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Distinct miRNA signatures associate with subtypes of cholangiocarcinoma from infection with the tumourigenic liver fluke Opisthorchis viverrini [PDF]

, 2014
Background & Aims: Intrahepatic cholangiocarcinoma (ICC) is a significant public health problem in East Asia, where it is strongly associated with chronic infection by the food-borne parasite Opisthorchis viverrini (OV). We report the first comprehensive
Bethony, Jeffrey M., Bhudhisawasdi, Vajarabhongsa, Brindley, Paul J., Easley, Samantha, Feng, Yanjun, Laha, Therawach, Mulvenna, Jason P., Pairojkul, Chawalit, Peng, Jin, Plieskatt, Jordan L., Rinaldi, Gabriel, Sripa, Banchob, Yonglitthipagon, Ponlapat   +12 more
core   +1 more source

Emulating Six Cardiovascular Outcome Trials of Antidiabetic Drugs in Individuals with Type 2 Diabetes: Analyses Based on Real‐World Databases from Korea and Taiwan

Clinical Pharmacology &Therapeutics, EarlyView.
With the increasing volume of clinical evidence derived from large‐scale Asian real‐world data (RWD) and the growing interest in its use in regulatory decision‐making, it is important to conduct benchmarking exercises that evaluate whether studies using Asian RWD can generate similar conclusions as randomized controlled trials (RCTs).
Hwa Yeon Ko, Philip C. M. Au, Michael Chun‐Yuan Cheng, Ching‐Lung Cheung, Ahhyung Choi, Miyuki Hsing‐Chun Hsieh, Han Eol Jeong, Edward Chia‐Cheng Lai, Brian Meng‐Hsun Li, Kenneth K. C. Man, Jeremy A. Rassen, Daniel Hsiang‐Te Tsai, Shirley V. Wang, Ian C. K. Wong, Ju‐Young Shin, Sohee Park   +15 more
wiley   +1 more source

A Downmodulated MicroRNA Profiling in Patients with Gastric Cancer

Gastroenterology Research and Practice, 2017
Objective. Here, we aim to investigate the microRNA (miR) profiling in human gastric cancer (GC). Methods. Tumoral and matched peritumoral gastric specimens were collected from 12 GC patients who underwent routine surgery.
Tao Zhang, Chang Liu, Shi Huang, Yuanping Ma, Jiansong Fang, Yuanneng Chen   +5 more
doaj   +1 more source

Hsa-let-7c-5p, hsa-miR-130b-3p, and hsa-miR-142-3p as Novel miRNA Biomarkers for Melanoma Progression

Genetics Research, 2022
This study aimed to screen miRNA biomarkers for melanoma progression. Raw melanoma data were downloaded from the Gene Expression Omnibus (GSE34460, GSE35579, GSE18509, and GSE24996) and the Cancer Genome Atlas (TCGA).
Xuerui Wu, Yu Wang, Chen Chen, Yadong Xue, Shuyun Zheng, Limin Cai   +5 more
doaj   +1 more source

Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-Viral hsa-miR-132 Processing in CEM-SS Cells [PDF]

Background: Despite tremendous advances in antiretroviral therapy (ART) against HIV-1 infections, no cure or vaccination is available. Therefore, discovering novel therapeutic strategies remains an urgent need.
Aathma Bejoy, Andreas Brunschweiger, Christine Leemann, Helen Lightfoot, Jeffrey Schloßhauer, Jochen Imig, Jonathan Hall, Karin Metzner, Seyedeh Banijamali, Shashank Tiwari, Valentina Vongrad, Verena Schlösser   +11 more
core   +1 more source

A Review of Black Phosphorus‐Based Materials: From Preparation Strategies to Characterization Techniques

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The structure, properties, preparation methods, and characterization techniques of BP. As a typical 2D layered material, black phosphorus (BP) demonstrates exceptional promise in various fields, particularly in energy storage for alkali metal‐ion batteries. However, its distinctive structure and properties, together with the compositional complexity of
Yunqing Wang, Jinzhi Lyu, Yongxiang Li, Yubing Wang, Xiangming Cui, Jianan Wang, Banglong Wan, Wei Yan   +7 more
wiley   +1 more source

BRAF(V600) inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells [PDF]

, 2019
The BRAF inhibitors vemurafenib and dabrafenib can be used to treat patients with metastatic melanomas harboring BRAF(V600) mutations. Initial antitumoral responses are often seen, but drug-resistant clones with reactivation of the MEK-ERK pathway soon ...
Bagge, Roger Olofsson, Cheng, Lesley, Einarsdottir, Berglind O., Gho, Yong Song, Hill, Andrew F., Lasser, Cecilia, Lotvall, Jan, Lunavat, Taral R., Muralidharan, Somsundar Veppil, Nilsson, Jonas A., Sharples, Robyn A.   +10 more
core   +1 more source