Extracellular microRNAs modulate human microglial function through TLR8
ObjectiveMicroRNAs (miRNAs) are abundantly expressed in the brain and are specifically dysregulated in central nervous system (CNS) diseases. They act as post-transcriptional gene regulators but can also serve as ligands for Toll-like receptors (TLRs ...
Hannah Weidling +22 more
doaj +1 more source
Plasma miR-22-5p, miR-132-5p, and miR-150-3p Are Associated with Acute Myocardial Infarction [PDF]
Huixian Li +6 more
openalex +1 more source
Background Myocardial infarction (MI) is a major cause of mortality and morbidity worldwide. The intercellular communication in post-infarction angiogenesis remains unclear.
Hongzhou Guo +3 more
doaj +1 more source
miR-132-3p靶向调控PTEN/Akt信号通路对缺氧/复氧诱导海马神经元HT22细胞损伤的影响
目的 研究miR-132-3p靶向调控第10号染色体缺失的磷酸酶基因(PTEN)/蛋白激酶B(Akt)信号通路对缺氧/复氧(H/R)诱导海马神经元HT22细胞损伤的影响。方法 体外培养HT22细胞并随机分为对照组、H/R组、阴性对照(miR-132-3p mimics阴性对照+空载质粒)组、miR-132-3p mimics组(miR-132-3p mimics)、PTEN敲低组(PTEN siRNA质粒)、miR-132-3p mimics+PTEN过表达组(miR-132-3p mimics ...
程宝仓, 齐林, 曾利敏
doaj
Association between miR-138-5p, miR-132-3p, SIRT1, STAT3, and CD36 and atherogenic indices in blood mononuclear cells from patients with atherosclerosis [PDF]
Samira Ehsani +3 more
openalex +1 more source
miRNA Expression and HCC Occurrence in HCV Cirrhotic Patients Treated with Direct Acting Antivirals [PDF]
Background: The risk of hepatocarcinoma in HCV cirrhotic patient responders after treatment with DAAs decrease, but HCC still occurs. A correlation between specific miRNAs and the development of hepatocarcinoma have been highlighted.
Andreone P. +19 more
core +1 more source
Background Sarcoidosis and tuberculosis (TB) are the two most common causes of granulomatous mediastinal lymphadenopathy. These often exhibit overlapping clinical and radiological characteristics, rendering accurate diagnosis difficult.
Bijay Pattnaik +12 more
doaj +1 more source
Long non-coding RNA SND1-IT1 accelerates cell proliferation, invasion and migration via regulating miR-132-3p/SMAD2 axis in retinoblastoma. [PDF]
Yin DF, Zhou XJ, Li N, Liu HJ, Yuan H.
europepmc +1 more source
Sepsis-associated acute kidney injury in mice and humans elicits heterogeneous renal microvascular microRNA responses [PDF]
Microvascular endothelial cells play important roles in sepsis-associated acute kidney injury (SA-AKI). In this study, we focused on microvascular microRNAs changes following SA-AKI to identify microRNAs as novel druggable targets and microvasculature ...
Bouma, Hjalmar R +12 more
core +1 more source

