Results 161 to 165 of about 21,775 (165)
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Pulmonary Pharmacology & Therapeutics, 2020
Dihydroquercetin (DHQ) is a potent flavonoid which has been demonstrated to have multiple biological activities including anti-inflammation activity, antioxidant activity as well as anti-cancer activity etc. Recently, many studies have focused on the antioxidant activity of DHQ.
Jian-Hua, Liu +5 more
openaire +2 more sources
Dihydroquercetin (DHQ) is a potent flavonoid which has been demonstrated to have multiple biological activities including anti-inflammation activity, antioxidant activity as well as anti-cancer activity etc. Recently, many studies have focused on the antioxidant activity of DHQ.
Jian-Hua, Liu +5 more
openaire +2 more sources
Biochemical and Biophysical Research Communications, 2020
Recent evidence has revealed a novel signaling mechanism through which brown adipose tissue (BAT)-derived exosomal microRNAs (miRNAs) influence hepatic gene expression. Here, we uncover neuronal control of these miRNAs and identify exosomal miR-132-3p as a regulator of hepatic lipogenesis under cold stress conditions.
Yuichi Kariba +5 more
openaire +2 more sources
Recent evidence has revealed a novel signaling mechanism through which brown adipose tissue (BAT)-derived exosomal microRNAs (miRNAs) influence hepatic gene expression. Here, we uncover neuronal control of these miRNAs and identify exosomal miR-132-3p as a regulator of hepatic lipogenesis under cold stress conditions.
Yuichi Kariba +5 more
openaire +2 more sources
Neurotoxicity Research, 2020
Clinical application of local anesthetic reagent, liposomal bupivacaine (BUP), may cause irreversible damage to human nerve system. In this study, we explored the functional role of long non-coding RNA (lncRNA) small nucleolar RNA host gene 16 (SNHG16) in BUP-induced neurotoxicity in SH-SY5Y cells.
Lei, Guan, Tianzuo, Li, Jingwen, Jiang
openaire +2 more sources
Clinical application of local anesthetic reagent, liposomal bupivacaine (BUP), may cause irreversible damage to human nerve system. In this study, we explored the functional role of long non-coding RNA (lncRNA) small nucleolar RNA host gene 16 (SNHG16) in BUP-induced neurotoxicity in SH-SY5Y cells.
Lei, Guan, Tianzuo, Li, Jingwen, Jiang
openaire +2 more sources
Experimental Neurology
Vascular dementia (VD) is accompanied by severe neuronal damage. Exosomal microRNAs (miRs) have been implicated in the neuroprotective effect of neural stem cells (NSCs), and miR-132-3p is a proneurogenic miR. In this study, we aimed to explore the role and underlying mechanisms of miR-132-3p-enriched NSC-EXs in VD-induced neuronal damage and synaptic ...
Yan, Wang +8 more
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Vascular dementia (VD) is accompanied by severe neuronal damage. Exosomal microRNAs (miRs) have been implicated in the neuroprotective effect of neural stem cells (NSCs), and miR-132-3p is a proneurogenic miR. In this study, we aimed to explore the role and underlying mechanisms of miR-132-3p-enriched NSC-EXs in VD-induced neuronal damage and synaptic ...
Yan, Wang +8 more
openaire +2 more sources
Rheumatology
Abstract Objective This study examines how exosomal miR-132-3p from M1 macrophages contributes to the development of systemic lupus erythematosus (SLE)-associated DAH and the molecular mechanisms involved.
Xun Chen +5 more
openaire +1 more source
Abstract Objective This study examines how exosomal miR-132-3p from M1 macrophages contributes to the development of systemic lupus erythematosus (SLE)-associated DAH and the molecular mechanisms involved.
Xun Chen +5 more
openaire +1 more source