Results 11 to 20 of about 21,775 (165)

Circ_DOCK1 regulates USP11 through miR-132-3p to control colorectal cancer progression [PDF]

World Journal of Surgical Oncology, 2021
Background Circular RNAs (circRNAs) take part in colorectal cancer malignancies. CircRNA dedicator of cytokinesis 1 (circ_DOCK1) is involved in colorectal cancer progression, but the mechanism underlying this circRNA that takes part in colorectal cancer ...
Weitong Zhang, Zhenfen Wang, Guohao Cai, Ping Huang   +3 more
doaj   +5 more sources

Circulating miR-132-3p as a Candidate Diagnostic Biomarker for Malignant Mesothelioma. [PDF]

Dis Markers, 2017
The use of circulating microRNAs as biomarkers has opened new opportunities for diagnosis of cancer because microRNAs exhibit tumor-specific expression profiles. The aim of this study was the identification of circulating microRNAs in human plasma as potential biomarkers for the diagnosis of malignant mesothelioma.
Weber DG, Gawrych K, Casjens S, Brik A, Lehnert M, Taeger D, Pesch B, Kollmeier J, Bauer TT, Johnen G, Brüning T.   +10 more
europepmc   +8 more sources

circRNF20 aggravates the malignancy of retinoblastoma depending on the regulation of miR-132-3p/PAX6 axis [PDF]

Open Medicine, 2022
Circular RNAs (circRNAs) serve as essential players in diverse human cancers, including retinoblastoma (RB). In this study, the function of circRNA Ring Finger Protein 20 (circRNF20) in RB progression was investigated.
An Dexiang, Yang Jing, Ma Linli
doaj   +4 more sources

MiR-132-3p suppresses peritoneal fibrosis induced by peritoneal dialysis via targeting TGF-β1/Smad2/3 signaling pathway. [PDF]

PLoS ONE
BackgroundPeritoneal fibrosis (PF) is the main complication of peritoneal dialysis (PD) and the most common cause of cessation from PD. There is still no effective therapeutic approach to reserve PF.
Yangyang Yin, Yuqi Yang, Yongqiang Zhang, Yu Shang, Qian Li, Jing Yuan   +5 more
doaj   +4 more sources

LncRNA XIST knockdown alleviates LPS-induced acute lung injury by inactivation of XIST/miR-132-3p/MAPK14 pathway : XIST promotes ALI via miR-132-3p/MAPK14 axis. [PDF]

Mol Cell Biochem, 2021
Acute lung injury (ALI) is a fatal inflammatory response syndrome. LncRNA XIST (XIST) is a lung cancer-related gene and participates in pneumonia. However, whether XIST participates in lipopolysaccharides (LPS)-induced ALI remains unclear. LPS-induced inflammation model was constructed in vitro, then cell viability, cytokines, cell apoptosis, protein ...
Li C, Liu JH, Su J, Lin WJ, Zhao JQ, Zhang ZH, Wu Q.   +6 more
europepmc   +5 more sources

miR-132-3p regulates antibody-mediated complement-dependent cytotoxicity in colon cancer cells by directly targeting CD55. [PDF]

Clin Exp Immunol, 2023
AbstractThe overexpression of membrane-bound complement regulatory proteins (mCRPs) on tumour cells helps them survive complement attacks by suppressing antibody-mediated complement-dependent cytotoxicity (CDC). Consequently, mCRP overexpression limits monoclonal antibody drug immune efficacy.
Fan Y, Liao J, Wang Y, Wang Z, Zheng H, Wang Y.   +5 more
europepmc   +4 more sources

MBNL1-AS1 Promotes Hypoxia-Induced Myocardial Infarction via the miR-132-3p/RAB14/CAMTA1 Axis. [PDF]

Oxid Med Cell Longev, 2023
Background. Mounting evidence have indicated that long noncoding RNA (lncRNA) muscleblind like splicing regulator 1 antisense RNA 1 (MBNL1-AS1) play a crucial regulatory role in cardiovascular disease, myocardial infarction (MI) included. In this research, we sought to probe into the biological function and potential mechanism of MBNL1-AS1 in MI ...
Li Y, Zong M, Guan X, Wu X, Ma G, Wei Y, Li Z.   +6 more
europepmc   +5 more sources

miR-132–3p is down-regulated in plasma and CD171+ extracellular vesicles isolated from patients with mild Alzheimer’s disease [PDF]

Mechanisms of Ageing and Development
Alzheimer’s disease (AD), the most prevalent neurodegenerative disorder in aging populations, demands minimally invasive biomarkers for early diagnosis and monitoring. Circulating microRNAs (miRNAs) show promise as such biomarkers.
Matilde Sbriscia, Tatiana Spadoni, Patrizia Ambrogini, Michele Guescini, Rachele Agostini, Laura Graciotti, Francesco Piacenza, Cinzia Giuli, Monia Cecati, Anna Rita Bonfigli, Salvatore Vaiasicca, Marica Pagliarini, Iryna Rusanova, Francesca Fazioli, Jacopo Sabbatinelli, Maria Cristina Albertini, Olivieri Fabiola, Angelica Giuliani   +17 more
core   +8 more sources

Brain microRNAs are associated with variation in cognitive trajectory in advanced age [PDF]

Translational Psychiatry, 2022
In advancing age, some individuals maintain a stable cognitive performance over time, while others experience a rapid decline. Such variation in cognitive trajectory is only partially explained by common neurodegenerative pathologies.
Aliza P. Wingo, Mengli Wang, Jiaqi Liu, Michael S. Breen, Hyun-Sik Yang, Beisha Tang, Julie A. Schneider, Nicholas T. Seyfried, James J. Lah, Allan I. Levey, David A. Bennett, Peng Jin, Philip L. De Jager, Thomas S. Wingo   +13 more
doaj   +2 more sources

Effect of miR-132-3p on epithelial-mesenchymal transition of trophoblast cells by targeting the SIRT1/NF-κB pathway [PDF]

Jichu yixue yu linchuang
Objective To investigate the effect of miR-132-3p on epithelial-mesenchymal transition (EMT) of trophoblast cells through targeted regulation of the SIRT1/NF-κB pathway.
GUO Shuhuan, GAO Yali, CHEN Jingge
doaj   +2 more sources