Reduction of miR‑132‑3p contributes to gastric cancer proliferation by targeting MUC13. [PDF]
Abnormal expression of epidermal growth factor receptor (EGFR) signaling and microRNAs (miRNAs) has been widely seen in gastric cancer. The present study focused on the miRNAs that regulate human epidermal growth factor receptor (HER) activation through mucin 13 (MUC13).
He L, Qu L, Wei L, Chen Y, Suo J.
europepmc +6 more sources
Exosomes isolated from mesenchymal stem cells (MSC) had shown beneficial effect on acute lung injury (ALI). However, the effective components in MSC-derived exosomes need further investigation.
Jian-Hua Liu +4 more
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Background: Although the changes of mitogen-activated protein kinase (MAPK) pathway in the central nervous system (CNS) induced by excessive fluoride has been confirmed by our previous findings, the underlying mechanism(s) of the action remains unclear ...
Wen-Wen He +11 more
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Tribbles-1 Expression and Its Function to Control Inflammatory Cytokines, Including Interleukin-8 Levels are Regulated by miRNAs in Macrophages and Prostate Cancer Cells [PDF]
The pseudokinase TRIB1 controls cell function in a range of contexts, by regulating MAP kinase activation and mediating protein degradation via the COP1 ubiquitin ligase.
Chiara Niespolo +8 more
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Overexpression of microRNAs miR-25-3p, miR-185-5p and miR-132-3p in Late Onset Fetal Growth Restriction, Validation of Results and Study of the Biochemical Pathways Involved. [PDF]
Loscalzo G +8 more
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Suppression of Foxo3-Gatm by miR-132-3p Accelerates Cyst Formation by Up-Regulating ROS in Autosomal Dominant Polycystic Kidney Disease. [PDF]
Choi S, Kim DY, Ahn Y, Lee EJ, Park JH.
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Mechanism of miR-132-3p Promoting Neuroinflammation and Dopaminergic Neurodegeneration in Parkinson's Disease. [PDF]
The major pathology in Parkinson’s disease (PD) is neuron injury induced by degeneration of dopaminergic neurons and the activation of microglial cells. The objective of this study is to determine the effect and mechanism of miR-132-3p in regulating neuroinflammation and the degeneration of dopaminergic neuron in PD.
Gong X, Huang M, Chen L.
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Long Non-Coding RNA SNHG16 Activates USP22 Expression to Promote Colorectal Cancer Progression by Sponging miR-132-3p. [PDF]
He X, Ma J, Zhang M, Cui J, Yang H.
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Interfering hsa_circ_0073748 alleviates caerulein-induced ductal cell injury in acute pancreatitis by inhibiting miR-132-3p/TRAF3/NF-κB pathway. [PDF]
Ren S +8 more
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miR-132-3p靶向调控PTEN/Akt信号通路对缺氧/复氧诱导海马神经元HT22细胞损伤的影响 附视频
目的 研究miR-132-3p靶向调控第10号染色体缺失的磷酸酶基因(PTEN)/蛋白激酶B(Akt)信号通路对缺氧/复氧(H/R)诱导海马神经元HT22细胞损伤的影响。方法 体外培养HT22细胞并随机分为对照组、H/R组、阴性对照(miR-132-3p mimics阴性对照+空载质粒)组、miR-132-3p mimics组(miR-132-3p mimics)、PTEN敲低组(PTEN siRNA质粒)、miR-132-3p mimics+PTEN过表达组(miR-132-3p mimics ...
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