Results 21 to 30 of about 21,775 (165)

Reduction of miR‑132‑3p contributes to gastric cancer proliferation by targeting MUC13. [PDF]

open access: hybridMol Med Rep, 2017
Abnormal expression of epidermal growth factor receptor (EGFR) signaling and microRNAs (miRNAs) has been widely seen in gastric cancer. The present study focused on the miRNAs that regulate human epidermal growth factor receptor (HER) activation through mucin 13 (MUC13).
He L, Qu L, Wei L, Chen Y, Suo J.
europepmc   +6 more sources

Exosomal miR-132-3p from mesenchymal stem cells alleviated LPS-induced acute lung injury by repressing TRAF6

open access: yesAutoimmunity, 2021
Exosomes isolated from mesenchymal stem cells (MSC) had shown beneficial effect on acute lung injury (ALI). However, the effective components in MSC-derived exosomes need further investigation.
Jian-Hua Liu   +4 more
doaj   +3 more sources

Regulating effect of miR-132–3p on the changes of MAPK pathway in rat brains and SH-SY5Y cells exposed to excessive fluoride by targeting expression of MAPK1

open access: goldEcotoxicology and Environmental Safety
Background: Although the changes of mitogen-activated protein kinase (MAPK) pathway in the central nervous system (CNS) induced by excessive fluoride has been confirmed by our previous findings, the underlying mechanism(s) of the action remains unclear ...
Wen-Wen He   +11 more
doaj   +2 more sources

Tribbles-1 Expression and Its Function to Control Inflammatory Cytokines, Including Interleukin-8 Levels are Regulated by miRNAs in Macrophages and Prostate Cancer Cells [PDF]

open access: yesFrontiers in Immunology, 2020
The pseudokinase TRIB1 controls cell function in a range of contexts, by regulating MAP kinase activation and mediating protein degradation via the COP1 ubiquitin ligase.
Chiara Niespolo   +8 more
doaj   +3 more sources

Overexpression of microRNAs miR-25-3p, miR-185-5p and miR-132-3p in Late Onset Fetal Growth Restriction, Validation of Results and Study of the Biochemical Pathways Involved. [PDF]

open access: goldInt J Mol Sci, 2021
Loscalzo G   +8 more
europepmc   +3 more sources

Mechanism of miR-132-3p Promoting Neuroinflammation and Dopaminergic Neurodegeneration in Parkinson's Disease. [PDF]

open access: yeseNeuro, 2022
The major pathology in Parkinson’s disease (PD) is neuron injury induced by degeneration of dopaminergic neurons and the activation of microglial cells. The objective of this study is to determine the effect and mechanism of miR-132-3p in regulating neuroinflammation and the degeneration of dopaminergic neuron in PD.
Gong X, Huang M, Chen L.
europepmc   +4 more sources

miR-132-3p靶向调控PTEN/Akt信号通路对缺氧/复氧诱导海马神经元HT22细胞损伤的影响 附视频

open access: greenZhongguo shiyan zhenduanxue
目的 研究miR-132-3p靶向调控第10号染色体缺失的磷酸酶基因(PTEN)/蛋白激酶B(Akt)信号通路对缺氧/复氧(H/R)诱导海马神经元HT22细胞损伤的影响。方法 体外培养HT22细胞并随机分为对照组、H/R组、阴性对照(miR-132-3p mimics阴性对照+空载质粒)组、miR-132-3p mimics组(miR-132-3p mimics)、PTEN敲低组(PTEN siRNA质粒)、miR-132-3p mimics+PTEN过表达组(miR-132-3p mimics ...
doaj   +3 more sources

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