Results 21 to 30 of about 54,811 (219)

LncRNA SNHG5 affects cell proliferation, metastasis and migration of colorectal cancer through regulating miR-132-3p/CREB5. [PDF]

Cancer Biol Ther, 2019
We aimed at the effects of long non-coding RNA (lncRNA) SNHG5 on proliferation, metastasis and migration of colorectal cancer (CRC) cells. We also investigated regulatory relationships among miR-132-3p, SNHG5 and CREB5 and their roles in CRC. 25 pairs of
Zhang M, Li Y, Wang H, Yu W, Lin S, Guo J.   +5 more
europepmc   +5 more sources

Genomic gain/methylation modification/hsa-miR-132-3p increases RRS1 overexpression in liver hepatocellular carcinoma. [PDF]

Cancer Sci, 2023
This study aimed to determine the upstream regulatory factors affecting ribosome biogenesis regulator 1 homolog (RRS1) expression and the development and prognosis of liver hepatocellular carcinoma (LIHC).
Zhang X, Cong P, Tian L, Zheng Y, Zhang H, Liu Q, Wu T, Zhang Q, Wu H, Huang X, Xiong L.   +10 more
europepmc   +2 more sources

Brain microRNAs are associated with variation in cognitive trajectory in advanced age [PDF]

Translational Psychiatry, 2022
In advancing age, some individuals maintain a stable cognitive performance over time, while others experience a rapid decline. Such variation in cognitive trajectory is only partially explained by common neurodegenerative pathologies.
Aliza P. Wingo, Mengli Wang, Jiaqi Liu, Michael S. Breen, Hyun-Sik Yang, Beisha Tang, Julie A. Schneider, Nicholas T. Seyfried, James J. Lah, Allan I. Levey, David A. Bennett, Peng Jin, Philip L. De Jager, Thomas S. Wingo   +13 more
doaj   +2 more sources

Circulating miR-132-3p as a Candidate Diagnostic Biomarker for Malignant Mesothelioma. [PDF]

Dis Markers, 2017
The use of circulating microRNAs as biomarkers has opened new opportunities for diagnosis of cancer because microRNAs exhibit tumor-specific expression profiles. The aim of this study was the identification of circulating microRNAs in human plasma as potential biomarkers for the diagnosis of malignant mesothelioma.
Weber DG, Gawrych K, Casjens S, Brik A, Lehnert M, Taeger D, Pesch B, Kollmeier J, Bauer TT, Johnen G, Brüning T.   +10 more
europepmc   +6 more sources

Expression Analysis of hsa-miR-181a-5p, hsa-miR-143-3p, hsa-miR-132-3p and hsa-miR-23a-3p as Biomarkers in Colorectal Cancer-Relationship to the Body Mass Index. [PDF]

Cancers (Basel), 2023
Simple Summary Colorectal cancer (CRC) is one of the main tumor pathologies in our society considering its incidence and mortality. Various authors have linked the development of CRC with overweight and obesity.
Tesolato SE, González-Gamo D, Barabash A, Claver P, de la Serna SC, Domínguez-Serrano I, Dziakova J, de Juan C, Torres AJ, Iniesta P.   +9 more
europepmc   +2 more sources

miR‐132‐3p promotes heat stimulation‐induced esophageal squamous cell carcinoma tumorigenesis by targeting KCNK2

Molecular Carcinogenesis, 2023
Epidemiological evidence supports that consumption of high‐temperature food and beverages is an important risk factor for esophageal squamous cell carcinoma (ESCC); however, the underlying mechanism still remains unclear. Here, we established a series of
Jing Wang, Jiaqiong Li, D. Cheng, Keke Zhang, Wenting Liu, Qianqian Xue, R. Du, Liting Zhou, Yiu To Yeung, Ruihua Bai, Hui Huang, J. Cui, P. Xiang, Yafei Zhi, Kangdong Liu, Xiang Li, Z. Dong   +16 more
semanticscholar   +3 more sources

miR-132-3p Modulates DUSP9-Dependent p38/JNK Signaling Pathways to Enhance Inflammation in the Amnion Leading to Labor. [PDF]

Int J Mol Sci, 2022
Labor is a process of inflammation and hormonal changes involving both fetal and maternal compartments. MicroRNA-132-3p (miR-132-3p) has been reported to be involved in the development of inflammation-related diseases.
Zhong Z, Liu Z, Zheng R, Chai J, Jiang S.   +4 more
europepmc   +2 more sources

LncRNA TUG1 mediates ischemic myocardial injury by targeting miR-132-3p/HDAC3 axis. [PDF]

American Journal of Physiology-Heart and Circulatory Physiology, 2019
BACKGROUND Increased production of reactive oxygen species (ROS) significantly contributed to the pathogenesis of acute myocardial infarction (AMI). Recent studies suggest that hypoxia up-regulated the long non-coding RNA taurine up-regulated gene 1 ...
Q. Su, Yang Liu, Xiangwei Lv, Rixin Dai, Xiheng Yang, Binghui Kong   +5 more
semanticscholar   +3 more sources

Regulating effect of miR-132–3p on the changes of MAPK pathway in rat brains and SH-SY5Y cells exposed to excessive fluoride by targeting expression of MAPK1

Ecotoxicology and Environmental Safety
Background: Although the changes of mitogen-activated protein kinase (MAPK) pathway in the central nervous system (CNS) induced by excessive fluoride has been confirmed by our previous findings, the underlying mechanism(s) of the action remains unclear ...
Wen-Wen He, Xiao-Xiao Zeng, Xiao-Lan Qi, Chuan-Zhi Gui, Wei Liao, Xi Tu, Jie Deng, Yang-Ting Dong, Wei Hong, Yan He, Yan Xiao, Zhi-Zhong Guan   +11 more
doaj   +2 more sources

Tribbles-1 Expression and Its Function to Control Inflammatory Cytokines, Including Interleukin-8 Levels are Regulated by miRNAs in Macrophages and Prostate Cancer Cells [PDF]

Frontiers in Immunology, 2020
The pseudokinase TRIB1 controls cell function in a range of contexts, by regulating MAP kinase activation and mediating protein degradation via the COP1 ubiquitin ligase.
Chiara Niespolo, Jessica M. Johnston, Sumeet R. Deshmukh, Swapna Satam, Ziyanda Shologu, Oscar Villacanas, Ian M. Sudbery, Heather L. Wilson, Endre Kiss-Toth   +8 more
doaj   +3 more sources