Integrated analysis of miRNAs and DNA methylation identifies miR‐132‐3p as a tumor suppressor in lung adenocarcinoma [PDF]
Thoracic Cancer, 2020 Background Aberrant miRNA expression and DNA methylation are two major epigenetic events in lung adenocarcinoma (LUAD). We conducted a combined analysis of the molecular changes in LUAD.
Yun Su, Amol Shetty, Feng Jiang
doaj +2 more sources
Acta Biochimica Polonica, 2022 OBJECTIVE colorectal cancer (CRC) is a common cancer with high mortality. This study aimed to investigate the role of microRNA (miR)-132-3p on proliferation, invasion and migration of CRC cells.
Rui-Ying Huang +5 more
semanticscholar +3 more sources
Long Non-Coding RNA TUG1 Promotes Proliferation and Inhibits Apoptosis of Osteosarcoma Cells by Sponging miR-132-3p and Upregulating SOX4 Expression. [PDF]
Yonsei Med J, 2018 Purpose Long non-coding RNA taurine upregulated gene 1 (TUG1) is reported to be a vital regulator of the progression of various cancers. This study aimed to explore the exact roles and molecular mechanisms of TUG1 in osteosarcoma (OS) development ...
Li G, Liu K, Du X.
europepmc +2 more sources
MiR-193b-3p and miR-132-3p as prognostic biomarkers of survival in pleural mesothelioma patients treated with first-line bevacizumab plus pemetrexed-platinum chemotherapy in the IFCT-0701 MAPS phase 3 trial. [PDF]
Transl OncolLevallet G +17 more
europepmc +2 more sources
[MiR-132-3p negatively regulates CAMTA1 to promote Schwann cell proliferation and migration and alleviates I-125 seeds-induced exacerbation of facial nerve injury in rats]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhu J +6 more
europepmc +2 more sources
Extracellular microRNAs modulate human microglial function through TLR8 [PDF]
Frontiers in ImmunologyObjectiveMicroRNAs (miRNAs) are abundantly expressed in the brain and are specifically dysregulated in central nervous system (CNS) diseases. They act as post-transcriptional gene regulators but can also serve as ligands for Toll-like receptors (TLRs ...
Hannah Weidling +22 more
doaj +2 more sources
The Stress-Responding miR-132-3p Shows Evolutionarily Conserved Pathway Interactions. [PDF]
Cell Mol Neurobiol, 2018 MicroRNAs (miRNAs) are small non-coding RNA chains that can each interact with the 3'-untranslated region of multiple target transcripts in various organisms, humans included. MiRNAs tune entire biological pathways, spanning stress reactions, by regulating the stability and/or translation of their targets.
Haviv R, Oz E, Soreq H.
europepmc +4 more sources
Increased miR-132-3p expression is associated with chronic neuropathic pain. [PDF]
Exp Neurol, 2016 Alterations in the neuro-immune balance play a major role in the pathophysiology of chronic neuropathic pain. MicroRNAs (miRNA) can regulate both immune and neuronal processes and may function as master switches in chronic pain development and maintenance.
Leinders M +4 more
europepmc +6 more sources
Functional involvement of septal miR-132 in extinction and oxytocin-mediated reversal of social fear [PDF]
, 2023 Social interactions are critical for mammalian survival and evolution. Dysregulation of social behavior often leads to psychopathologies such as social anxiety disorder, denoted by intense fear and avoidance of social situations.
Bludau, Anna +6 more
core +1 more source
Reduction of miR‑132‑3p contributes to gastric cancer proliferation by targeting MUC13. [PDF]
Mol Med Rep, 2017 Abnormal expression of epidermal growth factor receptor (EGFR) signaling and microRNAs (miRNAs) has been widely seen in gastric cancer. The present study focused on the miRNAs that regulate human epidermal growth factor receptor (HER) activation through mucin 13 (MUC13).
He L, Qu L, Wei L, Chen Y, Suo J.
europepmc +4 more sources