Results 51 to 60 of about 21,775 (165)

Music-listening regulates human microRNA expression

Epigenetics, 2021
Music-listening and performance have been shown to affect human gene expression. In order to further elucidate the biological basis of the effects of music on the human body, we studied the effects of music-listening on gene regulation by sequencing ...
Preethy Sasidharan Nair, Pirre Raijas, Minna Ahvenainen, Anju K. Philips, Liisa Ukkola-Vuoti, Irma Järvelä   +5 more
doaj   +1 more source

Circular RNA DOCK1 promotes bladder carcinoma progression via modulating circDOCK1/hsa-miR-132-3p/Sox5 signalling pathway. [PDF]

Cell Prolif, 2019
AbstractObjectivesTo reveal the role of circular RNA (circRNA) DOCK1 (circDOCK1) as a potential biomarker and therapeutic target and its competing endogenous RNA mechanism in bladder carcinoma (BC).MethodsThe next‐generation sequencing (NGS) technology was introduced to screen the circRNA expression profiles of BC using microarray.
Liu P, Li X, Guo X, Chen J, Li C, Chen M, Liu L, Zhang X, Zu X.   +8 more
europepmc   +4 more sources

Pathogenetic and diagnostic significance of microRNA deregulation in peripheral T-cell lymphoma not otherwise specified [PDF]

, 2014
Peripheral T-cell lymphomas not otherwise specified (PTCLs/NOS) are rare and aggressive tumours whose molecular pathogenesis and diagnosis are still challenging.
Agostinelli, C., Bacci, E., Barrese, T., Clò, A., Croce, C., Etebari, M., Fuligni, F., Gazzola, A., Gibellini, D., Inghirami, G., Laginestra, M., Mannu, C., Melle, F., Motta, G., Piccaluga, P., Pileri, S., Righi, S., Rossi, M., Sabattini, E., Sacchetti, C., Sapienza, M., Tabanelli, V., TRIPODO, Claudio   +22 more
core   +3 more sources

Three hematologic/immune system-specific expressed genes are considered as the potential biomarkers for the diagnosis of early rheumatoid arthritis through bioinformatics analysis

Journal of Translational Medicine, 2021
Background Rheumatoid arthritis (RA) is the most common chronic autoimmune connective tissue disease. However, early RA is difficult to diagnose due to the lack of effective biomarkers.
Qi Cheng, Xin Chen, Huaxiang Wu, Yan Du
doaj   +1 more source

Circulating MicroRNAs as Quantitative Biomarkers for Diagnosis and Prognosis of Uveal Melanoma

Frontiers in Oncology, 2022
For uveal melanoma (UM) patients, it is significant to establish diagnosis and prognosis evaluation systems through imaging techniques. However, imaging examinations are short of quantitative biomarkers and it is difficult to finish early diagnosis of UM.
Wen-Da Zhou, Lei Shao, Li Dong, Rui-Heng Zhang, Yi-Fan Li, He-Yan Li, Hao-Tian Wu, Xu-Han Shi, Wen-Bin Wei   +8 more
doaj   +1 more source

Age-Related Changes in MicroRNA Expression and Pharmacogenes in Human Liver [PDF]

, 2015
Developmental changes in the liver can significantly impact drug disposition. Due to the emergence of microRNAs (miRNAs) as important regulators of drug disposition gene expression, we studied age-dependent changes in miRNA expression.
Benson, Eric A., Burgess, Kimberly S., Desta, Zeruesenay, Gaedigk, Andrea, Gaedigk, Roger, Liu, Yunlong, Philips, Santosh, Segar, Matthew W., Skaar, Todd C.   +8 more
core   +1 more source

Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells

Scientific Reports, 2023
Endothelial dysfunction and inflammatory immune response trigger dedifferentiation of vascular smooth muscle cells (SMCs) from contractile to synthetic phenotype and initiate arterial occlusion.
Yerin Kim, Namhee Yu, Ye Eun Jang, Eunkyung Lee, Yeonjoo Jung, Doo Jae Lee, W. Robert Taylor, Hanjoong Jo, Jaesang Kim, Sanghyuk Lee, Sang Won Kang   +10 more
doaj   +1 more source

Mir-132/212 is required for maturation of binocular matching of orientation preference and depth perception [PDF]

, 2017
MicroRNAs (miRNAs) are known to mediate post-transcriptional gene regulation, but their role in postnatal brain development is still poorly explored. We show that the expression of many miRNAs is dramatically regulated during functional maturation of the
AN Lamb, B Bhaumik, B Scholl, BC Skottun, BH Miller, BS Wang, BS Wang, C Blakemore, C-É Stephany, CL McCurry, CM Niell, CN Levelt, D Tropea, DP Bartel, E Kang, E Sun, G Feng, G Schratt, GA Wayman, H Bokil, H Bridge, H Daoud, H Ko, H Ko, J Hernandez-Rapp, J Remenyi, JA Heimel, JC Dugas, JL Hoy, JS Espinosa, K Krishnan, K Wibrand, KA Rauen, KF Hansen, KF Hansen, L Baroncelli, L Baroncelli, L Cancedda, L Zhang, M He, M Pecka, MA Kayala, MG Butler, N Mellios, N Vo, NL Rochefort, O Issler, P Baldi, P Medini, P Tognini, P Tognini, P Tognini, P Tognini, R Sarnaik, RE Amir, S Impey, S Pichler, SA Buffington, SJ Kuhlman, T Iwasato, T Iwasato, TJ Lambert, V Anttila, V Porciatti, W Wang, X Zhao, Y Kobayashi, Y Tsurusaki   +67 more
core   +3 more sources

Differential expression of microRNAs in bovine papillomavirus type 1 transformed equine cells [PDF]

, 2016
Bovine papillomavirus (BPV) types 1 and 2 play an important role in the pathogenesis of equine sarcoids (ES), the most common cutaneous tumour affecting horses.
Britton, C., Nasir, L., Nicolson, L., Terron-Canedo, N., Weir, W.   +4 more
core   +1 more source

LncRNA NEAT1 regulates apoptosis in Parkinson's disease via sponging miR-132-3p

, 2022
Abstract Emerging studies have indicated that dysregulation of long non-coding RNA nuclear-enriched assembly transcript 1 (lncRNA NEAT1) is closely associated with development of Parkinson’s disease (PD). But the potential mechanism of NEAT1 is unclear.
Anmu Xie, Yumei Liu, Weichao Yao, Jing Gao, Liying Yang   +4 more
openaire   +1 more source