Results 51 to 60 of about 54,811 (219)

Three hematologic/immune system-specific expressed genes are considered as the potential biomarkers for the diagnosis of early rheumatoid arthritis through bioinformatics analysis

Journal of Translational Medicine, 2021
Background Rheumatoid arthritis (RA) is the most common chronic autoimmune connective tissue disease. However, early RA is difficult to diagnose due to the lack of effective biomarkers.
Qi Cheng, Xin Chen, Huaxiang Wu, Yan Du
doaj   +1 more source

Age-Related Changes in MicroRNA Expression and Pharmacogenes in Human Liver [PDF]

, 2015
Developmental changes in the liver can significantly impact drug disposition. Due to the emergence of microRNAs (miRNAs) as important regulators of drug disposition gene expression, we studied age-dependent changes in miRNA expression.
Benson, Eric A., Burgess, Kimberly S., Desta, Zeruesenay, Gaedigk, Andrea, Gaedigk, Roger, Liu, Yunlong, Philips, Santosh, Segar, Matthew W., Skaar, Todd C.   +8 more
core   +1 more source

Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells

Scientific Reports, 2023
Endothelial dysfunction and inflammatory immune response trigger dedifferentiation of vascular smooth muscle cells (SMCs) from contractile to synthetic phenotype and initiate arterial occlusion.
Yerin Kim, Namhee Yu, Ye Eun Jang, Eunkyung Lee, Yeonjoo Jung, Doo Jae Lee, W. Robert Taylor, Hanjoong Jo, Jaesang Kim, Sanghyuk Lee, Sang Won Kang   +10 more
doaj   +1 more source

Mir-132/212 is required for maturation of binocular matching of orientation preference and depth perception [PDF]

, 2017
MicroRNAs (miRNAs) are known to mediate post-transcriptional gene regulation, but their role in postnatal brain development is still poorly explored. We show that the expression of many miRNAs is dramatically regulated during functional maturation of the
AN Lamb, B Bhaumik, B Scholl, BC Skottun, BH Miller, BS Wang, BS Wang, C Blakemore, C-É Stephany, CL McCurry, CM Niell, CN Levelt, D Tropea, DP Bartel, E Kang, E Sun, G Feng, G Schratt, GA Wayman, H Bokil, H Bridge, H Daoud, H Ko, H Ko, J Hernandez-Rapp, J Remenyi, JA Heimel, JC Dugas, JL Hoy, JS Espinosa, K Krishnan, K Wibrand, KA Rauen, KF Hansen, KF Hansen, L Baroncelli, L Baroncelli, L Cancedda, L Zhang, M He, M Pecka, MA Kayala, MG Butler, N Mellios, N Vo, NL Rochefort, O Issler, P Baldi, P Medini, P Tognini, P Tognini, P Tognini, P Tognini, R Sarnaik, RE Amir, S Impey, S Pichler, SA Buffington, SJ Kuhlman, T Iwasato, T Iwasato, TJ Lambert, V Anttila, V Porciatti, W Wang, X Zhao, Y Kobayashi, Y Tsurusaki   +67 more
core   +3 more sources

Differential expression of microRNAs in bovine papillomavirus type 1 transformed equine cells [PDF]

, 2016
Bovine papillomavirus (BPV) types 1 and 2 play an important role in the pathogenesis of equine sarcoids (ES), the most common cutaneous tumour affecting horses.
Britton, C., Nasir, L., Nicolson, L., Terron-Canedo, N., Weir, W.   +4 more
core   +1 more source

LncRNA NEAT1 regulates apoptosis in Parkinson's disease via sponging miR-132-3p

, 2022
Abstract Emerging studies have indicated that dysregulation of long non-coding RNA nuclear-enriched assembly transcript 1 (lncRNA NEAT1) is closely associated with development of Parkinson’s disease (PD). But the potential mechanism of NEAT1 is unclear.
Anmu Xie, Yumei Liu, Weichao Yao, Jing Gao, Liying Yang   +4 more
openaire   +1 more source

Association between miR-138-5p, miR-132-3p, SIRT1, STAT3, and CD36 and atherogenic indices in blood mononuclear cells from patients with atherosclerosis

Egyptian Journal of Medical Human Genetics, 2023
Developed countries have a high mortality rate from atherosclerosis and are frequently linked to inflammation and other blood lipid disorders. MicroRNA expression can affect atherosclerotic plaque formation, lipid metabolism, inflammation, and other ...
Samira Ehsani, Maysam Mard-Soltani, Fatemeh Ahmadpour, Gholamreza Shahsavari   +3 more
semanticscholar   +1 more source

Maternal recognition of pregnancy in the horse : are MicroRNAs the secret messengers? [PDF]

, 2020
The signal for maternal recognition of pregnancy (MRP) has still not been identified in the horse. High-throughput molecular biology at the embryo-maternal interface has substantially contributed to the knowledge on pathways affected during MRP, but an ...
Deforce, Dieter, Gansemans, Yannick, Gerits, Ilse, Govaere, Jan, Peelman, Luc, Roels, Kim, Smits, Katrien, Tilleman, Laurentijn, Van de Velde, Margot, Van Nieuwerburgh, Filip, Van Soom, Ann, Ververs, Cyrillus   +11 more
core   +2 more sources

Early MicroRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection [PDF]

, 2014
It is not currently possible to predict the probability of whether a woman with a chlamydial genital infection will develop pelvic inflammatory disease (PID).
Adams, NE, Bowlin, A, Cleves, MA, Creasy, HH, Maurelli, AT, McChesney, GR, Myers, GSA, Rank, RG, Ravel, J, Spencer, N, Yeruva, L   +10 more
core   +2 more sources

Unraveling Molecular Pathways Altered in MeCP2-Related Syndromes, in the Search for New Potential Avenues for Therapy [PDF]

, 2021
Methyl-CpG-binding protein 2 (MeCP2) is an X-linked epigenetic modulator whose dosage is critical for neural development and function. Loss-of-function mutations in MECP2 cause Rett Syndrome (RTT, OMIM #312750) while duplications in the Xq28 locus ...
Alcántara Horrillo, Soledad, Armstrong, Judith, Balada, Rafel, Castells, Aina-Alba, Cortès i Saladelafont, Elisenda, Garcia Cazorla, Àngels, O’Callaghan, Mar, Pascual Alonso, Ainhoa, Tristán Noguero, Alba   +8 more
core   +1 more source