Results 61 to 70 of about 54,811 (219)

miR-9-5p, miR-124-3p, and miR-132-3p regulate BCL2L11 in tuberous sclerosis complex angiomyolipoma [PDF]

open access: yesLaboratory Investigation, 2018
Tuberous sclerosis complex (TSC) is a genetic disorder characterized by tumor formation in multiple organs, with over 80% of TSC patients developing angiomyolipomas (TSC-AMLs). However, the molecular events that contribute to TSC-AMLs are not well understood.
Yi, Cai   +5 more
openaire   +2 more sources

Involvement of miR-106b in tumorigenic actions of both prolactin and estradiol. [PDF]

open access: yes, 2017
Prolactin promotes a variety of cancers by an array of different mechanisms. Here, we have investigated prolactin's inhibitory effect on expression of the cell cycle-regulating protein, p21.
Bustamante, Karissa   +3 more
core   +1 more source

Alteration of the microRNA network during the progression of Alzheimer's disease

open access: yesEMBO Molecular Medicine, 2013
An overview of miRNAs altered in Alzheimer's disease (AD) was established by profiling the hippocampus of a cohort of 41 late‐onset AD (LOAD) patients and 23 controls, showing deregulation of 35 miRNAs.
Pierre Lau   +17 more
doaj   +1 more source

The Lin28/Let-7 system in early human embryonic tissue and ectopic pregnancy. [PDF]

open access: yesPLoS ONE, 2014
Our objective was to determine the expression of the elements of the Lin28/Let-7 system, and related microRNAs (miRNAs), in early stages of human placentation and ectopic pregnancy, as a means to assess the potential role of this molecular hub in the ...
Teresa Lozoya   +15 more
doaj   +1 more source

Altered microRNA and target gene expression related to Tetralogy of Fallot [PDF]

open access: yes, 2019
MicroRNAs (miRNAs) play an important role in guiding development and maintaining function of the human heart. Dysregulation of miRNAs has been linked to various congenital heart diseases including Tetralogy of Fallot (TOF), which represents the most ...
Appelt, Sandra   +4 more
core   +2 more sources

Are circulating microRNAs suitable for the early detection of malignant mesothelioma? Results from a nested case–control study

open access: yesBMC Research Notes, 2019
Objective Malignant mesothelioma is an aggressive cancer of the serous membranes. For the detection of the tumor at early stages non- or minimally-invasive biomarkers are needed.
Daniel Gilbert Weber   +9 more
doaj   +1 more source

Identification of the miRNA-mRNA regulatory network associated with radiosensitivity in esophageal cancer based on integrative analysis of the TCGA and GEO data

open access: yesBMC Medical Genomics, 2022
Background The current study set out to identify the miRNA-mRNA regulatory networks that influence the radiosensitivity in esophageal cancer based on the The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) databases.
Hongmin Chen   +8 more
doaj   +1 more source

Electrocatalytic Reduction of CO2 to Ethylene: Catalyst Design and Synchrotron‐Based Characterizations

open access: yesAdvanced Functional Materials, EarlyView.
This review evaluates strategies for electrochemical CO2 reduction to ethylene, focusing on copper‐based catalyst design and microenvironment modulation to achieve industrial‐grade performance. By leveraging operando synchrotron‐based characterizations, we provide a multiscale understanding of dynamic structural transformations and key reaction ...
Meng Zhang, Zuolong Chen, Yimin A. Wu
wiley   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

open access: yesAdvanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello   +2 more
wiley   +1 more source

Heterophase fcc‐hcp‐fcc High‐Entropy Alloy Nanomaterials with Tailored Electron Divergence for Selective Ammonia Electrosynthesis

open access: yesAdvanced Materials, EarlyView.
Heterophase fcc‐hcp‐fcc RuFeMMnMo (M═CoNi, Co, and Ni) high‐entropy alloy nanomaterials have been successfully synthesized using a one‐pot approach. The highly random distribution of multiple metal components and the tunable diversity of metal atomic arrangements can be realized simultaneously. By combining metals with different work functions, fcc‐hcp‐
Xiang Meng   +18 more
wiley   +1 more source

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