Results 61 to 70 of about 21,775 (165)

Maternal recognition of pregnancy in the horse : are MicroRNAs the secret messengers? [PDF]

open access: yes, 2020
The signal for maternal recognition of pregnancy (MRP) has still not been identified in the horse. High-throughput molecular biology at the embryo-maternal interface has substantially contributed to the knowledge on pathways affected during MRP, but an ...
Deforce, Dieter   +11 more
core   +2 more sources

Early MicroRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection [PDF]

open access: yes, 2014
It is not currently possible to predict the probability of whether a woman with a chlamydial genital infection will develop pelvic inflammatory disease (PID).
Adams, NE   +10 more
core   +2 more sources

MiR-132-3p inhibits proliferation, invasion and migration of colorectal cancer cells via down-regulating FOXP2 expression

open access: yesActa Biochimica Polonica, 2022
Objective: colorectal cancer (CRC) is a common cancer with high mortality. This study aimed to investigate the role of microRNA (miR)-132-3p on proliferation, invasion and migration of CRC cells. Materials and Methods: qRT-PCR and Western blot analyses were used to determine the expression of miR-132-3p and forking box (FOX) protein 2 (FOXP2) in CRC ...
Rui, Huang   +5 more
openaire   +2 more sources

Involvement of miR-106b in tumorigenic actions of both prolactin and estradiol. [PDF]

open access: yes, 2017
Prolactin promotes a variety of cancers by an array of different mechanisms. Here, we have investigated prolactin's inhibitory effect on expression of the cell cycle-regulating protein, p21.
Bustamante, Karissa   +3 more
core   +1 more source

Unraveling Molecular Pathways Altered in MeCP2-Related Syndromes, in the Search for New Potential Avenues for Therapy [PDF]

open access: yes, 2021
Methyl-CpG-binding protein 2 (MeCP2) is an X-linked epigenetic modulator whose dosage is critical for neural development and function. Loss-of-function mutations in MECP2 cause Rett Syndrome (RTT, OMIM #312750) while duplications in the Xq28 locus ...
Alcántara Horrillo, Soledad   +8 more
core   +1 more source

Alteration of the microRNA network during the progression of Alzheimer's disease

open access: yesEMBO Molecular Medicine, 2013
An overview of miRNAs altered in Alzheimer's disease (AD) was established by profiling the hippocampus of a cohort of 41 late‐onset AD (LOAD) patients and 23 controls, showing deregulation of 35 miRNAs.
Pierre Lau   +17 more
doaj   +1 more source

The Lin28/Let-7 system in early human embryonic tissue and ectopic pregnancy. [PDF]

open access: yesPLoS ONE, 2014
Our objective was to determine the expression of the elements of the Lin28/Let-7 system, and related microRNAs (miRNAs), in early stages of human placentation and ectopic pregnancy, as a means to assess the potential role of this molecular hub in the ...
Teresa Lozoya   +15 more
doaj   +1 more source

Altered microRNA and target gene expression related to Tetralogy of Fallot [PDF]

open access: yes, 2019
MicroRNAs (miRNAs) play an important role in guiding development and maintaining function of the human heart. Dysregulation of miRNAs has been linked to various congenital heart diseases including Tetralogy of Fallot (TOF), which represents the most ...
Appelt, Sandra   +4 more
core   +2 more sources

Are circulating microRNAs suitable for the early detection of malignant mesothelioma? Results from a nested case–control study

open access: yesBMC Research Notes, 2019
Objective Malignant mesothelioma is an aggressive cancer of the serous membranes. For the detection of the tumor at early stages non- or minimally-invasive biomarkers are needed.
Daniel Gilbert Weber   +9 more
doaj   +1 more source

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