Results 251 to 260 of about 384,139 (274)

Increased plasma miR-370-3p expression in poor-outcome patients with pancreatic ductal adenocarcinoma.

Pancreatology, 2023
OBJECTIVE To determine whether circulating microRNAs (miRNAs) can be used as prognostic biomarkers for pancreatic ductal adenocarcinoma (PDAC). METHODS Patients with PDAC (N = 120) who underwent surgical resection at Hiroshima University Hospital ...
Takumi Harada, K. Uemura, Tatsuaki Sumiyoshi, Ryuta Shintakuya, K. Okada, Tetsuhiro Hara, Shinya Takahashi, E. Hiyama   +7 more
semanticscholar   +3 more sources

CIRC_0114428 INFLUENCES THE PROGRESSION OF SEPTIC ACUTE KIDNEY INJURY VIA REGULATING MIR-370-3P/TIMP2 AXIS

Shock, 2023
Background: Septic acute kidney injury (AKI) is a serious complication of sepsis, which greatly threatened the life safety of critically ill patients. Recently, circular RNA is considered to be implicated in sepsis-induced renal cell damage. However, the
Bihong Zhang, Ting You, Yu Liu, Pei Li
semanticscholar   +1 more source

CircSPI1_005 ameliorates osteoarthritis by sponging miR-370-3p to regulate the expression of MAP3K9

International Immunopharmacology, 2022
Osteoarthritis (OA), caused by the destruction of joint cartilage, is the most prevalent form of arthritis, causing pain and stiffness in joints among millions of patients worldwide. Increasing evidence suggests that non-coding RNAs, including circular RNAs, play important roles in the pathogenesis of OA, but the precise signaling pathway is still ...
Jian-Lin, Zhou, Shuang, Deng, Hong-Song, Fang, Hao, Peng, Qiong-Jie, Hu   +4 more
openaire   +2 more sources

Long Non-coding RNA XIST Impedes LPS-induced AC16 Cell Inflammation and Apoptosis through Down-regulating miR-370-3p and Regulating PI3K/AKT/mTOR Pathways.

Combinatorial chemistry & high throughput screening, 2023
BACKGROUND/PURPOSE Myocarditis is a severe disorder characterized by the inflammation of the heart's muscular walls, thereby leading to sudden death in young adults.
Jun Xiao, Min Qiu, M. Long, Shushu Zhou, Shouyu Guo, Shaohua Xu, Haitao Jiang   +6 more
semanticscholar   +1 more source

Circ_0026579 knockdown ameliorates lipopolysaccharide‐induced human lung fibroblast cell injury by regulating CXCR1 via miR‐370‐3p

Clinical and Experimental Pharmacology and Physiology, 2023
Pneumonia is an inflammatory disease in lower respiratory tracts and its development involves the regulation of RNAs. Circular RNAs are a class of RNA subgroups that can mediate the progression of pneumonia.
Yu Zhuang, Yuyun Yang, Li Peng
semanticscholar   +1 more source

A literature review on the role of miR-370 in disease

Gene Reports, 2016
Abstract MicroRNAs (miRNAs) are a class of small non-coding RNA molecules which regulate posttranscriptional events. Many studies have revealed that miRNAs have emerged as disease-suppressive molecules or oncomiRs by targeting disease oncogenes or suppressor genes. Therefore, miRNAs have become a hotspot in many researches.
Jie Zhu, Bin Zhang, Wenfeng Song, Xie Zhang, Lei Wang, Bowei Yin, Fangfang Zhu, Chaohui Yu, Hong Li   +8 more
openaire   +1 more source

Expression and diagnostic potential of circulating miR-107, miR-134-5p, miR-149-5p, miR-370-3p, and miR-221 in prostate cancer and benign prostatic hyperplasia: a preliminary study.

Archivio Italiano di Urologia e Andrologia
BACKGROUND MicroRNAs (miRNAs) have shown promise as diagnostic biomarkers for prostate cancer (PCa). This study aimed to evaluate the expression of miR-107, miR-134-5p, miR-149-5p, miR-370-3p, and miR-221 in whole blood to distinguish PCa from benign ...
Ali Akkoç, Hamiyet Eciroglu Sarban, Fatma Yıldız, Ozlem Ceren Gunizi, Murat Uçar   +4 more
semanticscholar   +1 more source

Mg-Cross-Linked Alginate Hydrogel Induces BMSC/Macrophage Crosstalk to Enhance Bone Tissue Regeneration via Dual Promotion of the Ligand-Receptor Pairing of the OSM/miR-370-3p-gp130 Signaling Pathway.

ACS Applied Materials and Interfaces
Macrophages play a pivotal role in the crosstalk between the immune and skeletal systems, while Mg-based biomaterials demonstrate immunomodulatory capabilities in this procedure.
Li Gu, Rui Huang, Ni Ni, Rong Zhou, Yun Su, Ping Gu, Dandan Zhang, Xianqun Fan   +7 more
semanticscholar   +1 more source

Polystyrene Nanoparticles-coated Astragalus Polysaccharides Affects the Development of Prostate Cancer by Regulating Glycolysis of DAP12/SYK Axis through miR-370

Pharmacognosy Magazine
Background This study aims to explore the use of polystyrene nanoparticles as a carrier to encapsulate astragalus polysaccharides and regulate the glycolytic pathway of the DNAX-activating protein of 12 kDa/spleen tyrosine kinase (DAP12/SYK) axis through
C. Gao, Zixiong Liu, Jiafu Tan
semanticscholar   +1 more source

Inhibitory Effect of Ginkgo biloba Extract on Oxidative Stress and Apoptosis of Myocardial Cells in Sepsis by Regulating miR-370/FOXO1

Science of Advanced Materials
This research was aimed to investigate the effects of Ginkgo biloba leaf extract on oxidative stress and apoptosis in septic cardiomyocytes, focusing on the role of the miR-370/FOXO1 regulatory pathway.
Hai Lin, Yunwei Rao, Ji-Young Yi
semanticscholar   +1 more source