Results 161 to 170 of about 319,034 (267)

Numerical and Experimental Study of Mixing Characteristics in a Spiral Micromixer

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Significant enhancement of mixing performance can be achieved by Dean vortices in spiral channels. In order to deeply explore the mixing mechanisms and variation laws in spiral micromixers, this work designed a spiral micromixer and adopted a combined method of experiments and numerical simulations to analyze the mixing performance and ...
Anming Yang, Shiqing Zheng
wiley   +1 more source

Diagnostic and prognostic potential of microRNA profiles in endometrioid endometrial cancer

Scientific Reports
Gene regulation is influenced by microRNAs (miRNAs), a class of non-coding RNAs currently being studied as biomarkers for various diseases. miRNAs, which act as regulators of gene expression and potential biomarkers, were profiled in endometrioid type ...
Yağmur Soykan, Atiye Seda Yar Saglam, Mehmet Arda Inan, Asiye Ugras Dikmen, Özlem Erdem, Mehmet Anıl Onan   +5 more
doaj   +1 more source

CircSOS2 promotes cervical squamous cell carcinoma by regulation of proliferation, cell cycle, apoptosis, migration, invasion, and glycolysis by targeting miR-543/FNDC3B axis

, 2021
Yingming Li, Yan Tang, Zhaoyi Li, Guoqi Hou, Xiulan Du   +4 more
openalex   +1 more source

P-543 The role of FMRP-associated microRNAs miR-125b and miR-132 and their target genes in the regulation of ovarian function [PDF]

, 2022
Adriana Vilkaite, Xuan Phuoc Nguyen, U Bender, Katrin Hinderhofer, T. Strowitzki, Julia Rehnitz   +5 more
openalex   +1 more source

An ontological morphological phylogenetic framework for living and extinct ray‐finned fishes (Actinopterygii)

The Anatomical Record, EarlyView.
Abstract The ray‐finned fishes include one out of every two species of living vertebrates on Earth and have an abundant fossil record stretching 380 million years into the past. The division of systematic knowledge of ray‐finned fishes between paleontologists working on extinct animals and neontologists studying extant species has obscured the ...
Jack Stack
wiley   +1 more source

Integrating exosome wide associations study and Mendelian randomization identified causal miRNAs for type 2 diabetes mellitus and its complications

Diabetology & Metabolic Syndrome
Background Type 2 diabetes mellitus (T2DM) and its complications, including diabetic lower extremity arterial disease (DLEAD) and diabetic foot (DF), impose significant health burdens worldwide.
Dong-Ling Li, Xin-Yi Ding, Qiao-Ling He, Wan-Hua Zhan, Juan Long, Mei-Nan He, Jia-Lu Zhang, Qing-Xiang Zeng, Na Lu, Yong-Qian Chi, Meng-Chen Zou   +10 more
doaj   +1 more source

Multi‐omic profiling reveals immune cell priming signature linked to lupus prognosis

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is a multi‐organ disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith, Dominic Sinibaldi, Saifur Rahman, Chia‐Chien Chiang, Anna M. Hansen, Jill Henault, Carlos P. Roca, Shu Wang, Kamelia Zerrouki, Rebecca Filippi, Christopher Groves, Zerai Manna, Jun Chu, Michael Davis, Sarthak Gupta, Christopher Morehouse, Melissa de los Reyes, Rachel Ettinger, Roland Kolbeck, Mariana J. Kaplan, Miguel A. Sanjuan, Richard M. Siegel, Sarfaraz A. Hasni, Kerry A. Casey   +23 more
wiley   +1 more source

Single‐cell level characterization of B cell depletion and repopulation following rituximab in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang, Norzawani Buang, Catherine Sutherland, Wanseon Lee, Lauren Overend, Tarran S. Rupall, Katie L. Burnham, Matthew C. Pickering, Marina Botto, Emma E. Davenport   +9 more
wiley   +1 more source

Validation of International Classification of Diseases (ICD) code‐based case definitions of immune checkpoint inhibitor associated inflammatory arthritis from administrative health data

Arthritis &Rheumatology, Accepted Article.
Background Immune checkpoint inhibitors (ICIs) for cancer can lead to immune‐related adverse events, including ICI‐associated inflammatory arthritis (ICI‐IA). There are no validated International Classification of Diseases (ICD) code–based case definitions for ICI‐IA.
Manar Elsayed, Zoe Hsu, Finlay A. McAlister, William D. Leslie, Lisa M. Lix, Sasha Bernatsky, Suzanne N Morin, Michelle M Graham, Aurore Fifi‐Mah, Shahin Jamal, Janet Roberts, Carrie Ye   +11 more
wiley   +1 more source

Trends in the utilization, expenditure and costs of noninsulin glucose‐lowering drugs in the Medicaid population: Steady increases in glucagon‐like peptide‐1 receptor agonist and sodium–glucose transporter‐2 inhibitor use, prices and expenditure

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley   +1 more source