Results 201 to 210 of about 6,191 (242)

Pharmacological Inhibition of APT2 by Solasonine Promotes Ferroptosis Through Palmitoylation Modulation in Gallbladder Cancer

open access: yesPhytotherapy Research, EarlyView.
Schematic illustration of SS‐induced ferroptosis through targeting APT2‐mediated STAT3 palmitoylation in GBC cells. ABSTRACT Gallbladder cancer (GBC), the most prevalent and lethal biliary tract malignancy, lacks effective therapeutic strategies. Solasonine (SS), a bioactive steroidal alkaloid derived from Solanum nigrum L, exhibits antitumor activity ...
Liu‐qing Shi   +12 more
wiley   +1 more source

Deep learning‐based ecological analysis of camera trap images is impacted by training data quality and quantity

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
Machine learning image classifiers are increasingly being used to automate camera trap image labelling, but we don't know how much ML model accuracy matters for downstream ecological analyses. Using two large data sets from an African savannah and an Asian dry forest ecosystem, we compared human labelled data with predictions from deep‐learning models ...
Peggy A. Bevan   +12 more
wiley   +1 more source

Are boards reluctant to remove poorly performing successors to interim CEOs?

open access: yesStrategic Management Journal, EarlyView.
Abstract Research Summary Interim CEO appointments are disruptive and costly to firms. Boards justify them as necessary to find the right permanent successor. But what happens if that successor performs poorly? This paper argues that directors may be reluctant to remove a poorly performing successor to an interim CEO early in their tenure.
Robert Langan
wiley   +1 more source

Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development

open access: yesSmall, EarlyView.
Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen   +7 more
wiley   +1 more source

Accelerated Catalyst Development via Kinetically Controlled Solid‐State Laser Synthesis and Automated Electrochemical Screening

open access: yesSmall, EarlyView.
A rapid laser‐based method produces metal nanoparticles on carbon under ambient conditions, eliminating the need for solvents and surfactants. By adjusting laser parameters, particle size and uniformity are precisely controlled and rapidly analyzed using X‐ray diffraction.
Mattis Goßler   +9 more
wiley   +1 more source

Two‐Stage Isothermal Transformation of Austenite into Nanobainite in a Chemically Inhomogeneous Medium‐Alloy Steel Containing 0.5 wt% C

open access: yessteel research international, EarlyView.
The effect of chemical inhomogeneity on the microstructure and properties of nanobainitic steel is investigated. A two‐stage isothermal heat treatment that produced a more uniform microstructure is designed. The first‐stage temperature is higher than the MS of depleted bands; conversely, the second‐stage temperature is lower than the first‐stage ...
Bogdan Garbarz   +5 more
wiley   +1 more source

1D and 3D Carbon Nanomaterials Derived from Zeolite‐Based Catalysts: Synthesis and Applications

open access: yesSmall Structures, EarlyView.
Zeolites act as catalysts or catalytic templates to synthesize 1D and 3D carbon nanomaterials with uniform structures, enabled by their high surface area and uniform porous frameworks. The resulting carbon nanomaterials possess excellent surface area and electronic conductivity, supporting their use in energy storage, catalysis, electronics, gas ...
Kulika Pithaksinsakul   +3 more
wiley   +1 more source

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