Results 31 to 40 of about 2,235,858 (234)
miR-544靶向DUSP13抑制神经胶质瘤细胞增殖、周期分布和凋亡
目的 探究miR-544在神经胶质母细胞瘤(Glioblastoma, GBM)细胞增殖中的作用及机制。方法 采用RT-qPCR检测miR-544及DUSP13在GBM组织和细胞中的表达。过表达miR-544后,CCK-8检测细胞活性变化;克隆形成实验检测细胞增殖能力,流式细胞仪检测细胞周期和凋亡。DUSP13与miR-544的靶向关系通过荧光素酶报告实验来证实。结果 GBM组织和细胞中miR-544表达显著低于癌旁组织和正常细胞 ...
何占彪, 王睿君
doaj
Non-alcoholic fatty liver disease (NAFLD) affects obesity-associated metabolic syndrome, which exhibits hepatic steatosis, insulin insensitivity and glucose intolerance.
Wencun Li (11353782) +6 more
core +1 more source
Non-alcoholic fatty liver disease (NAFLD) affects obesity-associated metabolic syndrome, which exhibits hepatic steatosis, insulin insensitivity and glucose intolerance.
Wencun Li (11353782) +6 more
core +1 more source
MicroRNAs at the human 14q32 locus have prognostic significance in osteosarcoma
Background Deregulation of microRNA (miRNA) transcript levels has been observed in many types of tumors including osteosarcoma. Molecular pathways regulated by differentially expressed miRNAs may contribute to the heterogeneous tumor behaviors observed ...
Sarver Aaron L +6 more
doaj +1 more source
miR449_string_hires_image-5-miR-449-miR-34.png
miR449_string_hires_image-5-miR-449-miR-34 ...
Federica Monaco (17674014)
core +1 more source
MicroRNAs in cardiac arrhythmia: DNA sequence variation of MiR-1 and MiR-133A in long QT syndrome. [PDF]
Long QT syndrome (LQTS) is a genetic cardiac condition associated with prolonged ventricular repolarization, primarily a result of perturbations in cardiac ion channels, which predisposes individuals to life-threatening arrhythmias.
Corfield, VA +13 more
core +1 more source
Background MicroRNAs (miRNAs) have been implicated in the regulation of milk protein synthesis and development of the mammary gland (MG). However, the specific functions of miRNAs in these regulations are not clear.
Li Zhen +4 more
doaj +1 more source
Background MicroRNAs (miRNAs) are small non-coding RNAs that participate in the spatiotemporal regulation of messenger RNA (mRNA) and protein synthesis.
Luo Zhaohui +10 more
doaj +1 more source
(a) Alignment between XLOC005698 and oar-miR-3955-5p as well as between XLOC000629 and oar-miR-544-5p. (b) The oar-miR-3955-5p miRNA binding sites on XLOC005698. (c)The oar-miR-544-5p miRNA binding sites on XLOC000629.
Tingting Guo (101831) +8 more
core +1 more source
Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection
ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd +118 more
wiley +1 more source

