Results 171 to 180 of about 4,615 (182)

QMR^® and Patient Blood-Derived Secretome Modulate RPE microRNA Networks Under Oxidative Stress. [PDF]

Int J Mol Sci
Alibrandi S, Mordà D, Scimone C, D'ascola A, Aliquò F, Pozzato A, Scalinci SZ, D'Angelo R, Sidoti A, Donato L.   +9 more
europepmc   +1 more source

The miRNA-immune axis in bladder cancer: systematic evidence for a new era of immunotherapy precision. [PDF]

Front Immunol
Dulf DV, Ravegnini G, Giorgi FM, Burnar AL, Gorini F, De Leo A, Luţichievici H, Opriţa CL, Todiruţ CN, Ciuleanu TE, Coadă CA.   +10 more
europepmc   +1 more source

Apoptosis-Related Non-Coding RNAs in Cardiac Fibrosis and Heart Failure: Implications for Pathogenesis and Therapy. [PDF]

J Inflamm Res
Wu H, Xia L, Liu C.
europepmc   +1 more source

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Clinical Value of Circulating ZFAS1 and miR-590-3p in the Diagnosis and Prognosis of Chronic Heart Failure

Cardiovascular Toxicology, 2021
Long non-coding RNAs (lncRNAs) have been reported to be involved in the development of various cardiovascular diseases, including chronic heart failure (CHF). In this study, we aimed to investigate the role of ZFAS1/miR-590-3p axis in the diagnosis and prognosis of CHF.
Gang Ding, Guannan Chang, Wenqing Zhang, Meicheng Zhang   +3 more
openaire   +3 more sources

MiR-590-3p Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells by Targeting Lysyl Oxidase

Journal of Cardiovascular Pharmacology, 2023
Abstract: We investigated the clinical characteristics of patients with acute aortic dissection (AAD) and miR-590-3p levels in serum, tissue, and vascular smooth muscle cells. The effect of miR-590-3p on the vascular smooth muscle cell phenotype was assessed, and the regulation of lysyl oxidase by miR-5903p was determined.
Lei, Wang, Lin, Zhang, Li-Kun, Cui, Xiao, Yue, Li, Huang, Na, Liu, Meng-Die, Zhu, Zheng-Bin, Wang   +7 more
openaire   +2 more sources

Exosomal LINC00161 promotes angiogenesis and metastasis via regulating miR-590-3p/ROCK axis in hepatocellular carcinoma

Cancer Gene Therapy, 2021
Hepatocellular carcinoma (HCC) is a lethal malignancy with few effective options for therapeutic treatment in its advanced stages. While exosomal LINC00161 has been identified as a potential biomarker for HCC, its regulatory function and clinical values remain largely unknown.
Li-Na You, Qin-Wen Tai, Wu-Kui Huang, Wu-Kui Huang, Yi Hao, Wen-Jia Guo, Lin Xu, Heng Zhang, Qing Tong, Qiao Zhang   +9 more
openaire   +3 more sources

Effect of miR-590-3p/DKK1 Axis on the Progression of Wilms’ Tumour

Archivos Españoles de Urología
Wilms' tumour is the most prevalent abdominal malignancy in children. This study focused on the mechanism of the miR-590-3p/Dickkopf 1 (DKK1) axis in Wilms' tumour.The mRNA levels of miR-590-3p and DKK1 in 49 pairs of Wilms' tumour pathological specimens and normal tissues were determined using real-time quantitative polymerase chain reaction (RT-qPCR).
Hong, Wang, Yiliang, Zhang
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MiR-590-3p regulates osteogenic differentiation of human mesenchymal stem cells by regulating APC gene

Biochemical and Biophysical Research Communications, 2016
The present study aimed to investigate miR-590-3p's role in osteogenic differentiation of human mesenchymal stem cells (hMSC). HMSC were cultured and transfected with empty vector, miR-590-3p vector to construct control hMSC and miR-590-3p overexpression hMSC. MiR-590-3p suppressed hMSC was created with oligonucleotide transient transfection.
Siyuan Wu, Weizhen Liu, Lei Zhou
openaire   +3 more sources