Results 41 to 50 of about 905,046 (159)

A microRNA signature associated with pathological complete response to novel neoadjuvant therapy regimen in triple-negative breast cancer

open access: yesTumor Biology, 2017
Neoadjuvant chemotherapy aims to improve the outcome of breast cancer patients, but only few would benefit from this treatment. Pathological complete response has been proposed as a surrogate marker for the prediction of long-term clinical benefits ...
Raúl García-Vazquez   +11 more
doaj   +1 more source

Dysregulated circRNA expression profile and associated miRNA sponging in abnormal lung development in congenital diaphragmatic hernia

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Circular RNAs (circRNAs) are stable, stage‐ and tissue‐specific regulators of gene expression warranting their study in abnormal fetal lung development in congenital diaphragmatic hernia (CDH). We present a CDH‐specific circRNA biosignature in the nitrofen rat model (E15/E21) using orthogonal validation with human comparison and discovered conserved ...
Marietta Jank   +16 more
wiley   +1 more source

Analysis of the Inhibitory Effect of hsa-miR-145-5p and hsa-miR-203a-5p on Imatinib-Resistant K562 Cells by GC/MS Metabolomics Method

open access: yes, 2023
Imatinib (IM) resistance is considered to be a significant challenge in the management of chronic myeloid leukemia (CML). Previous studies have reported that hsa-miR-145-5p and hsa-miR-203a-5p can overcome IM resistance and hsa-miR-203a-5p can alter ...
Priyanka Singh (256412)   +7 more
core   +1 more source

Identification and Validation of Dilated Cardiomyopathy-Related Genes via Bioinformatics Analysis

open access: yesInternational Journal of General Medicine, 2022
Li-Jun Wang,1,* Bai-Quan Qiu,1,* Ming-Ming Yuan,2,* Hua-Xi Zou,1 Cheng-Wu Gong,1 Huang Huang,2 Song-Qing Lai,3 Ji-Chun Liu1 1Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, People’s ...
Wang LJ   +7 more
doaj  

Potential Predictive Value of miR-125b-5p, miR-155-5p and Their Target Genes in the Course of COVID-19

open access: yes, 2022
Xuewen Li,1 Yiting Wang,1 Qi Zhou,2 Junqi Pan,3 Jiancheng Xu1 1Department of Laboratory Medicine, First Hospital of Jilin University, Changchun, People’s Republic of China; 2Department of Pediatrics, First Hospital of Jilin University, Changchun, People ...
Li X, Pan J, Zhou Q, Wang Y, Xu J
core  

DAMP Laden Extracellular Vesicles From the Airways of Patients With Severe SARS‐CoV‐2 Respiratory Infection Compromise Inflammation and Cellular Metabolism

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Extracellular vesicles from severe COVID‐19 airways carry depleted miRNAs and elevated DAMPs, reprogramming monocytes toward senescence, impaired metabolism, and predominantly reduced cytokine responses. However, they drive excess IL‐8 production, amplifying neutrophil recruitment and dysfunctional inflammation across the respiratory tract.
April Rees   +14 more
wiley   +1 more source

Bioinformatics predicted oar-miR-3955-5p binding sites on XLOC005698, and oar-miR-544-5p binding sites on XLOC000629.

open access: yes, 2016
(a) Alignment between XLOC005698 and oar-miR-3955-5p as well as between XLOC000629 and oar-miR-544-5p. (b) The oar-miR-3955-5p miRNA binding sites on XLOC005698. (c)The oar-miR-544-5p miRNA binding sites on XLOC000629.
Tingting Guo (101831)   +8 more
core   +1 more source

Gallic Acid‐Responsive microRNAs Reprogram Lignification During Drought Acclimation Process in Spearmint

open access: yesPlant Biotechnology Journal, Volume 24, Issue 6, Page 4263-4281, June 2026.
ABSTRACT Mentha spicata L. (spearmint) is a high‐value aromatic and medicinal species, whose productivity is strongly affected by water deficit. Nevertheless, the molecular mechanisms underlying drought acclimation in this mint remain largely unexplored. Thus, here, we investigated the microRNA‐mediated regulatory processes triggered in M.
Alessia D'Agostino   +7 more
wiley   +1 more source

Sero‐Epidemiology and Molecular Detection of Bluetongue Virus in Goats in Bangladesh

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
The first large‐scale study in Bangladesh confirmed bluetongue virus infection in goats through combined c‐ELISA and nested RT‐PCR approaches, revealing high seroprevalence and identifying key management‐related risk factors. ABSTRACT Background Bluetongue (BT) is an arthropod‐transmitted, non‐contagious viral disease of domestic ruminants caused by ...
Md Habibur Rahman   +5 more
wiley   +1 more source

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