Results 21 to 30 of about 905,046 (159)

Description of a CSF-Enriched miRNA Panel for the Study of Neurological Diseases

open access: yesLife, 2021
Background: The study of circulating miRNAs in CSF has gained tremendous attention during the last years, as these molecules might be promising candidates to be used as biomarkers and provide new insights into the disease pathology of neurological ...
María Muñoz-San Martín   +6 more
doaj   +1 more source

The Effect of miR-34a-5p and miR-145-5p Ectopic Expression on Cell Proliferation and Target Gene Expression in the MDA-MB-231 Cell Line [PDF]

open access: yes, 2021
Aim:It was aimed to investigate the effect of miR-34a-5p and miR-145-5p on breast cancer cell line MDA-MB-231 and to determine the expression of target genes of these microRNAs (miRNAs).Materials and Methods:Firstly, literature search and in silico ...
Emre ÖZGÜR   +5 more
core   +1 more source

Grouping Pentylenetetrazol-Induced Epileptic Rats According to Memory Impairment and MicroRNA Expression Profiles in the Hippocampus. [PDF]

open access: yesPLoS ONE, 2015
Previous studies have demonstrated a close relationship between abnormal regulation of microRNA (miRNA) and various types of diseases, including epilepsy and other neurological disorders of memory.
Xixia Liu   +5 more
doaj   +1 more source

Circulating microRNAs Suggest Networks Associated with Biological Functions in Aggressive Refractory Type 2 Celiac Disease

open access: yesBiomedicines, 2022
Despite following a gluten-free diet, which is currently the only effective therapy for celiac disease, about 5% of patients can develop serious complications, which in the case of refractory type 2 could evolve towards intestinal lymphoma. In this study,
Nicoletta Bianchi   +14 more
doaj   +1 more source

Circulating and urinary microRNAs profile for predicting renal recovery from severe acute kidney injury

open access: yesJournal of Intensive Care, 2022
Background There is little known about the contribution of microRNAs (miRNAs) in the recovery from acute kidney injury (AKI). This study aimed to discover and validate miRNA profiles for predicting renal recovery from severe AKI.
Thanawat Phulkerd   +9 more
doaj   +1 more source

Analyses of circRNAs profiles of the lactating and nonlactating crops in pigeon (Columba livia)

open access: yesPoultry Science, 2023
: Pigeon has the specific biological ability to produce pigeon milk (also known as crop milk) by its crop. Circular RNAs (circRNAs) are important noncoding RNAs acting as the sponges of miRNAs, but the molecular mechanism of circRNAs regulating crop milk
Hui Ma   +12 more
doaj   +1 more source

MicroRNA-770-5p contributes to podocyte injury via targeting E2F3 in diabetic nephropathy [PDF]

open access: yesBrazilian Journal of Medical and Biological Research
Diabetic nephropathy (DN) has been identified as the major cause of end-stage renal disease (ESRD) in most developed countries. MicroRNA-770-5p depletion could repress high glucose (HG)-triggered apoptosis in podocytes, and downregulation of E2F ...
Juanjuan Guo   +3 more
doaj   +2 more sources

Identifying prognostic lncRNAs based on a ceRNA regulatory network in laryngeal squamous cell carcinoma

open access: yesBMC Cancer, 2021
Purpose Growing evidence demonstrates that long non-coding RNAs (lncRNAs) play a crucial role as competing endogenous RNAs (ceRNAs) in tumor occurrence.
Yong Shi, Dongli Yang, Yixiao Qin
doaj   +1 more source

CircTPST2 inhibits cisplatin sensitivity in head and neck squamous cell carcinoma by sponging miR-770-5p and interacting with Nucleolin

open access: yes, 2023
Abstract Background: Head and neck squamous cell cancer (HNSCC) is the most prevalent head and neck malignancy. Chemoresistance is a major challenge in the treatment of advanced HNSCC. Circular RNAs (circRNAs) are essential for the development of cancer and chemoresistance.
Tianqing Wang   +15 more
openaire   +1 more source

miR-770-5p overexpression downregulated HER2 and increased the effect of trastuzumab.

open access: yes, 2019
(a) The protein expression level of HER2 was slightly diminished in both cell lines following miR-770-5p transfection n = 3, p(b) Combinational treatment of cells with trastuzumab and miR-770-5p decreased cell viability in BT-474 and SK-BR-3 cells (n = 3,
Bala Gur Dedeoglu (739961)   +2 more
core   +1 more source

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