Results 21 to 30 of about 905,046 (159)
Description of a CSF-Enriched miRNA Panel for the Study of Neurological Diseases
Background: The study of circulating miRNAs in CSF has gained tremendous attention during the last years, as these molecules might be promising candidates to be used as biomarkers and provide new insights into the disease pathology of neurological ...
María Muñoz-San Martín +6 more
doaj +1 more source
The Effect of miR-34a-5p and miR-145-5p Ectopic Expression on Cell Proliferation and Target Gene Expression in the MDA-MB-231 Cell Line [PDF]
Aim:It was aimed to investigate the effect of miR-34a-5p and miR-145-5p on breast cancer cell line MDA-MB-231 and to determine the expression of target genes of these microRNAs (miRNAs).Materials and Methods:Firstly, literature search and in silico ...
Emre ÖZGÜR +5 more
core +1 more source
Grouping Pentylenetetrazol-Induced Epileptic Rats According to Memory Impairment and MicroRNA Expression Profiles in the Hippocampus. [PDF]
Previous studies have demonstrated a close relationship between abnormal regulation of microRNA (miRNA) and various types of diseases, including epilepsy and other neurological disorders of memory.
Xixia Liu +5 more
doaj +1 more source
Despite following a gluten-free diet, which is currently the only effective therapy for celiac disease, about 5% of patients can develop serious complications, which in the case of refractory type 2 could evolve towards intestinal lymphoma. In this study,
Nicoletta Bianchi +14 more
doaj +1 more source
Background There is little known about the contribution of microRNAs (miRNAs) in the recovery from acute kidney injury (AKI). This study aimed to discover and validate miRNA profiles for predicting renal recovery from severe AKI.
Thanawat Phulkerd +9 more
doaj +1 more source
Analyses of circRNAs profiles of the lactating and nonlactating crops in pigeon (Columba livia)
: Pigeon has the specific biological ability to produce pigeon milk (also known as crop milk) by its crop. Circular RNAs (circRNAs) are important noncoding RNAs acting as the sponges of miRNAs, but the molecular mechanism of circRNAs regulating crop milk
Hui Ma +12 more
doaj +1 more source
MicroRNA-770-5p contributes to podocyte injury via targeting E2F3 in diabetic nephropathy [PDF]
Diabetic nephropathy (DN) has been identified as the major cause of end-stage renal disease (ESRD) in most developed countries. MicroRNA-770-5p depletion could repress high glucose (HG)-triggered apoptosis in podocytes, and downregulation of E2F ...
Juanjuan Guo +3 more
doaj +2 more sources
Purpose Growing evidence demonstrates that long non-coding RNAs (lncRNAs) play a crucial role as competing endogenous RNAs (ceRNAs) in tumor occurrence.
Yong Shi, Dongli Yang, Yixiao Qin
doaj +1 more source
Abstract Background: Head and neck squamous cell cancer (HNSCC) is the most prevalent head and neck malignancy. Chemoresistance is a major challenge in the treatment of advanced HNSCC. Circular RNAs (circRNAs) are essential for the development of cancer and chemoresistance.
Tianqing Wang +15 more
openaire +1 more source
miR-770-5p overexpression downregulated HER2 and increased the effect of trastuzumab.
(a) The protein expression level of HER2 was slightly diminished in both cell lines following miR-770-5p transfection n = 3, p(b) Combinational treatment of cells with trastuzumab and miR-770-5p decreased cell viability in BT-474 and SK-BR-3 cells (n = 3,
Bala Gur Dedeoglu (739961) +2 more
core +1 more source

