Results 181 to 190 of about 32,139,398 (268)

Circ_0024390 promotes renal tubular EMT through the miR-6890-3p/CHD4 axis: implications for renal interstitial fibrosis. [PDF]

Front Pharmacol
Yang X, Zhang L, Song Y, Liu G.
europepmc   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

A RARγ-SMARCA5 chromatin-remodeling axis stabilizes AR luminal programs and opposes lineage plasticity in prostate cancer. [PDF]

Nucleic Acids Res
Wani SA, Hussain S, Mir KB, Gray JS, Nayak D, Tang H, Perez LM, Long MD, Siddappa M, Corey E, Nelson PS, McCabe CJ, Sucheston-Campbell LE, Freeman MR, Campbell MJ.   +14 more
europepmc   +1 more source

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

FEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

The gene ivory:mir-193 controls scale type differentiation in Heliconius butterflies. [PDF]

Nat Commun
Hanly JJ, Camino L, Holder JC, Calderon-Oñate P, Wagh PR, Ruiz J, Zhao L, Stroh ED, Livraghi L, Loh LS, Arias CF, Gilbert LE, Wray GA, Martin A, McMillan WO.   +14 more
europepmc   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Construction and Evaluation of a Ketosis Prediction Model Based on Milk MIR Spectra and Feature Wavenumber Selection in Dairy Cows. [PDF]

Animals (Basel)
Ren X, Yang Z, Han A, Fan Y, Zhang Y, Chen S, Zhang Z, Yan L, Cao Z, Liu W, Huang X, Wang D, Zhang G, Yan Q, Zhang S.   +14 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Temporal Effects of Exogenous Testosterone on the Circulating Small Noncoding RNA Landscape in a Placebo‑Controlled Human Study. [PDF]

Andrology
Main AM, Solheim SA, Wagner SP, Albrechtsen HM, Nordsborg NB, Winge SB, Juul A, Mørup N, Almstrup K.   +8 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source