Results 221 to 230 of about 360,344 (284)

Mini‐Hairpin DNA: Extraordinarily Stable Structure and Its Applications

Chemistry – A European Journal, EarlyView.
Mini‐hairpin DNA fragments containing GCGAAGC and GCGAAAGC form exceptionally stable hairpin‐like structures, with only two G−C pairs and one sheared G−A pair, remaining undenatured in 7 M urea and resisting nuclease digestion. These mini‐hairpin sequences frequently appear in replication and transcription origins, influence DNA sequencing fidelity ...
Michiko Kimoto, Ichiro Hirao
wiley   +1 more source

The relationship between social adversity, micro-RNA expression and post-traumatic stress in a prospective, community-based cohort. [PDF]

Nat Ment Health
Wang C, Uddin M, Wani A, Graham Z, Ratanatharathorn A, Aiello AE, Koenen K, Maggio M, Wildman DE.   +8 more
europepmc   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

Analysis of EGFR signaling pathway; miRNAs and inflammatory biomarkers in a high-risk oral cancer population in Pakistan - An exploratory study. [PDF]

PLoS One
Anwar N, Pervez S, Moatter T, Stark M, Chundriger Q, Ali TS, Awan S, Antonsson A.   +7 more
europepmc   +1 more source

Articoli Schwarz(strand_seclection) / Grishok(stRNA&RNAi) / Han(microprocessor) [PDF]

, 2012
Danielli, Alberto
core  

Nanoparticles in microdroplets: Recent advances in microfluidic generators for producing functional microbeads

Droplet, EarlyView.
Functional hybrid microbeads with electrical, magnetic, and/or optical responsiveness have emerged as versatile platforms for biotechnology. This review highlights recent advances in microfluidic technologies for producing such microbeads, with a focus on incorporating functional nanoparticles in microdroplet systems.
  Bayinqiaoge, Chengchen Zhang, Shi‐Yang Tang   +2 more
wiley   +1 more source

Genome-wide analysis of conserved and novel miRNAs in mango mesocarp reveals early regulatory networks involved in postharvest heat stress response. [PDF]

Sci Rep
Dautt-Castro M, Cruz-Mendívil A, Ulloa-Álvarez L, Enríquez-Domínguez JA, Ávila-Sánchez M, Ulloa-Llanes LK, Casas-Flores S, Serafim TD, Islas-Osuna MA.   +8 more
europepmc   +1 more source

Identification of novel genes regulating the development of the palate

Developmental Dynamics, EarlyView.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

Landscape of microRNA and target expression variation and covariation in single mouse embryonic stem cells. [PDF]

Genome Res
Tarbier M, Mackowiak SD, Sekar V, Bonath F, Yapar E, Fromm B, Faridani OR, Biryukova I, Friedländer MR.   +8 more
europepmc   +1 more source