Results 1 to 10 of about 12,129 (122)

Adverse event reporting of mirtazapine: A disproportionality analysis of FDA adverse event reporting system (FAERS) database from 2004-2024. [PDF]

PLoS ONE
BackgroundMirtazapine is a pharmacological agent commonly utilized as a first-line treatment for major depressive disorder, exhibiting both noradrenergic and selective serotonergic activity.
Keying Guo, Haipeng Li, Wei Wang, Ling Cheng, Weina Du, Jing Zhang   +5 more
doaj   +2 more sources

Evaluation of the Short-Term Effects of Mirtazapine on Appetite Stimulants in Dogs: A Retrospective Study and a Placebo-Controlled Trial [PDF]

Animals
Anorexia and hyporexia are common clinical signs in dogs with acute or chronic illnesses, often requiring targeted nutritional interventions. Mirtazapine, an orexigenic drug widely used in cats, has limited evidence supporting its use in dogs. This study
Stephanie S. Theodoro, Maria Eduarda G. Tozato, Thais O. Ximenes, Lara M. Volpe, Camila Baptista da Silva, Fabio A. Teixeira, Aulus C. Carciofi   +6 more
doaj   +2 more sources

The cost of drug repurposing: parallel economic evaluation of mirtazapine for severe breathlessness in the multinational BETTER-B trial [PDF]

BMC Health Services Research
Background Breathlessness is a prevalent, distressing symptom in advanced respiratory disease. Proven treatments are lacking. Mirtazapine, an antidepressant, is increasingly prescribed.
Peter May, Charles Normand, Adejoke O. Oluyase, Samantha Smith, Sarah T. Brown, Matthew Maddocks, Massimo Costantini, Sabrina Bajwah, Kathrin Kahnert, Steffen T. Simon, Karen Ryan, David C. Currow, Miriam J. Johnson, Simon P. Hart, Małgorzata Krajnik, Silvia Tanzi, Charlotte E. Bolton, Piotr Janowiak, Elena Turola, Caroline J. Jolley, Hannah Mather, Geraldine Murden, Luca Ghirotto, Bobbie Farsides, Julia M. Brown, Irene J. Higginson, On behalf of the BETTER-B consortium   +26 more
doaj   +2 more sources

Atypical antidepressant mirtazapine inhibits 5-hydroxytryptamine3 receptor currents in NCB-20 cells

Journal of Pharmacological Sciences, 2023
Mirtazapine, an atypical antidepressant, is known to enhance serotonergic transmission by inhibiting the 5-hydroxytryptamine (5-HT)1A, 5-HT2C, and 5-HT3 receptors. However, the mechanism of action on the 5-HT3 receptor remains unclear.
Yong Soo Park, Haejung Oh, Ki-Wug Sung
doaj   +1 more source

Appetite Stimulant and Anti-Emetic Effect of Mirtazapine Transdermal Ointment in Cats Affected by Lymphoma Following Chemotherapy Administration: A Multi-Centre Retrospective Study

Animals, 2022
In humans, mirtazapine can prevent chemotherapy-induced nausea and vomiting (CINV) and improve cancer patients’ quality of life (QoL). This drug is being increasingly used as an appetite stimulant in cats.
Livia Ferro, Stefano Ciccarelli, Giacomo Stanzani, Lisa Nappi, Francesca Angelini, Chiara Leo   +5 more
doaj   +1 more source

Mirtazapine-induced neutropenic sepsis in an older person: a case report

Journal of Medical Case Reports, 2023
Background Mirtazapine is a frequently prescribed psychotropic drug for depression in older age. It is considered safe and has a side-effect profile uniquely favorable to an older person affected by reduced appetite, difficulty maintaining body weight ...
Alice Maidwell-Smith, Charlotte Kirk
doaj   +1 more source

The Antidepressant Mirtazapine Rapidly Shifts Hepatic B Cell Populations and Functional Cytokine Signatures in the Mouse

Frontiers in Immunology, 2021
IntroductionB cells are important regulators of both adaptive and innate immunity. The normal liver contains significant numbers of B cells, and their numbers increase dramatically in immune-mediated liver diseases.
Wagdi Almishri, Wagdi Almishri, Wagdi Almishri, Rachelle P. Davis, Rachelle P. Davis, Abdel-Aziz Shaheen, Mohammed O. Altonsy, Mohammed O. Altonsy, Mohammed O. Altonsy, Craig N. Jenne, Craig N. Jenne, Mark G. Swain, Mark G. Swain, Mark G. Swain   +13 more
doaj   +1 more source

Suvorexant and mirtazapine improve chronic pain-related changes in parameters of sleep and voluntary physical performance in mice with sciatic nerve ligation.

PLoS ONE, 2022
Both chronic pain and sleep disorders are associated with a reduction in the quality of life. They can be both a cause and a consequence of each other, and should therefore be simultaneously treated.
Hisakatsu Ito, Hiroshi Tsuneki, Toshiyasu Sasaoka, Naoki Toyooka, Mitsuhiro Matsuo, Mitsuaki Yamazaki   +5 more
doaj   +2 more sources

First-Degree Atrioventricular Block with Tachycardia from Paliperidone and Mirtazapine Overdose

European Journal of Case Reports in Internal Medicine, 2020
Background: Paliperidone and mirtazapine are psychotropic agents associated with proarrhythmic effects.  Case Presentation: A 21-year-old woman was admitted to the intensive care unit on two separate occasions for attempting suicide by overdosing on ...
Brian Cheung, Chris Levy, Abhijit Shivkumar   +2 more
doaj   +1 more source

Fabrication of Hydroxypropyl Methylcellulose Orodispersible Film Loaded Mirtazapine Using a Syringe Extrusion 3D Printer

Scientia Pharmaceutica, 2022
Depression is a mental illness causing a continuous negative feeling and loss of interest and affects physical and mental health. Mirtazapine (MTZ) is an effective medicine for treating depression, but patients lack compliance.
Tanpong Chaiwarit, Niphattha Aodsab, Pimonnart Promyos, Pattaraporn Panraksa, Suruk Udomsom, Pensak Jantrawut   +5 more
doaj   +1 more source